Infacare Pharmaceutical Corporation

Other

Acura Pharmaceuticals, Inc.

Wellspring Pharmaceutical Corporation

Halsey Drug Company, Inc.

Kazimierz Grzegorz Antczak

George S Drummond

Robert Caroselli

Benjamin Levinson

Richard Mortimer

Robert Vukovich

Vijai Kumar

Christopher P Boucher

Keith A Cooke

Charles Auxilium Francis

Zhaiwei Lin

Christopher Arne Kaldahl

Danny Levin

Daniel Levin

Christopher Boucher

Robert R Caroselli

Richard Donald Mortimer

A method of preparing metal mesoporphyrin halide compounds is described. The metal mesoporphyrin halide compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to the metal mesoporphyrin halide through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.

Preparation of metal mesoporphyrin compounds

A method of preparing metal mesoporphyrin compounds is described. A metal mesoporphyrin compound may be formed by forming a novel mesoporphyrin IX intermediate compound and then converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion. The novel intermediate compound may be formed by a catalytic hydrogenation of hemin in acid and subsequent recovery.

Oxycodone is manufactured in high yields and with a high purity using a composition including a thebaine component into 14-hydroxycodeinone and then reduction of 14-hydroxycodeinone to oxycodone.

Process for manufacturing opioid analgesics

Oxycodone is manufactured in high yields and with a high purity using codeine or a salt of codeine as the starting material. The manufacturing process involves the following steps:

Process for manufacturing oxycodone

Preparation of metal mesoporphyrin halide compounds

Process for manufacturing thebaine

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Culver, IN, United States of America

Kazimierz Grzegorz Antczak