Research Corporation Technologies, Inc.

Kay C Dee

Thomas T Andersen

Rena Bizios

Peptides containing the amino acid sequence, aa,-aa,-aa,-aa,-(Gly),, devices for implantation coated with the peptides and methods for altering cell adhesion using the peptides are disclosed. The residues aa,, aa,, and aa,are independently Lys, Arg, Orn or, when the residue is N-terminal, Acp. The residue aa,is Ala, Gly, Val, Leu, Ile, Ser, Thr, Cys, Met, Asn, Nle, Nva or Abu. The preferred sequence is KRSR. Peptides containing cell adhesion-related sequences can be incorporated into or coated onto substrates to enhance osteoblast adhesion.

Growing community of inventors

Troy, NY, United States of America

Kay C Dee