Asta Medica, Aktiengesellschaft

Arzneimittelwerk Dresden Gmbh

Paz Arzneimittelentwicklungsgesellschaft Mbh

Ludwig Heumann & Co. Gmbh

Meda Pharma Gmbh & Co. Kg

Valeant Pharmaceuticals North America

Ziophram Oncology, Inc.

Pharmatrans Sanaq Ag

Asta Medica Aktiengesellschgt

Kay Brune

Istvan Szelenyi

Peter Emig

Bernhard Kutscher

Hildegard Poppe

Stefan Szelenyi

Gerd Geisslinger

Rudolf Schindler

Dietmar Reichert

Guillaume Lebaut

Holger Bang

Helmut Schickaneder

Bernd Nickel

Kurt H Ahrens

Peter Morsdorf

Heidrun Engler

Gerhard Quinkert

Robert Hermann

Norbert Hofgen

Kurt H Bauer

Eckhard Günther

Norbert H&ouml;fgen

Jürgen Schmidt

Eckhard G&uuml;nther

Holger Deppe

J&uuml;rgen Schmidt

Istv&aacute;n Szel&eacute;nyi

Cécilia Menciu

Guillaume Le Baut

Anton S Huber

Mathia Locher

Mathias Locher

Gesa Tiegs

Albrecht Wendel

Dietmar Reichelt

Berhard Kutscher

Hans-G&uuml;nter Schaible

C&eacute;cilia Menciu

The invention relates to pharmaceutical combinations of potassium channel openers and sodium channel inhibitors, for treating pains which are accompanied by an increase in muscle tone.

Combinations of flupirtine and sodium channel inhibiting substances for treating pains

The invention relates to pharmaceutical combinations of retigabine and sodium channel inhibitors for treating pains which are accompanied by an increase in muscle tone.

Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains

The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents and to a pharmaceutical composition having antitumor action, characterized in that it contains at least one of the compounds of the general formula 1, if appropriate also in the form of the physiologically tolerable acid addition salts or N-oxides. Furthermore, the invention also includes antitumor agents comprising as active compound one or more N-substituted indole-3-glyoxylamides according to the general formula 1 and, if appropriate, their physiologically tolerable acid addition salts and, if possible, N-oxides and a pharmaceutically utilizable carrier and/or diluent or auxiliary substance in the form of tablets, coated tablets, capsules, solutions for infusion or ampoules, suppositories, patches, powder preparations which can be employed by inhalation, suspensions, creams and ointments.

Indolyl-3-glyoxylic acid derivatives having antitumor action

The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immuno-suppressant/immunomodulating actions.

N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action

The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immunosuppressant/immunomodulating actions.

The novel specific immunophilin ligands of the general formula I have an antiasthmatic and immunosuppressive action and are suitable for the preparation of drugs.

Specific immunophilin ligands as antiasthmatics and immunosuppressants

The invention relates to an immunophilin ligand of Formula I and having antiasthmatic, antiallergic, antirheumatic, immunosuppressant, antipsoriatic and neuroprotectant properties,

Immunophilin ligands

The invention relates to the use of N-substituted indole-3-glyoxylamides of the general formula I as antitumor agents

The invention relates to 1,2,5-trisubstituted 1,2-dihydroindazol-3-ones of formula (I)

1,2,5-trisubstituted 1,2-dihydroindazol-3-ones having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments

The invention relates to 1,5- and 3-O-substituted 1H-indazoles of formula (I) ##STR1##

1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic,

Process for the diagnostic assessment and monitoring, as well as

N-substituted indole-3 glyoxylamides having anti-asthmatic antiallergic

2-arylpropionic acid preparations and process for their production

The present invention provides a medicament for the treatment of painful and/or inflammatory diseases and/or of fever with flurbiprofen, wherein the previously separated enantiomers of flurbiprofen are worked up in a ratio of 99.5-0.5% to 0.5-99.5%, in combination with conventional pharmaceutical carriers and adjuvants, to give a medicament.

Medicament and its production and use in the treatment of pain,

Growing community of inventors

Marloffstein, Germany

Kay Brune