Centre National De La Recherche Scientifique

Université Paris—sud

Université Paris-Sud 11

Université Paris Sud Xi

Kawthar Bouchemal

Sebastien Pomel

Benedicte Pradines

Philippe Loiseau

Christian Bories

Christine Vauthier-Holtzscherer

Sébastien Pomel

Bénédicte Pradines

Microparticles and nanoparticles of hydrophobized polysaccharide and an alpha-cyclodextrin, obtained by self-association in an aqueous medium, the hydrophobized polysaccharide being obtained by grafting of alkyl chains derived from fatty acids, by an acylation reaction. These microparticles and nanoparticles constitute systems used for encapsulating substances of interest, in particular in the pharmaceutical field, and vectorization thereof for therapeutic purposes.

Microparticles and nanoparticles made up of hydrophobized polysaccharides and an alpha-cyclodextrine

A composition including hydrophobized chitosan can be used as an antiparasitic and/or antifungal agent or in the treatment of parasitic and/or fungal infections. The composition may include an antifungal agent and hydrophobized chitosan. The antifungal agent can be in association with the hydrophobized chitosan, with the latter being more preferably in the particle form, or the antifungal agent can be encapsulated in particles including the hydrophobized chitosan. The use of the composition as an antifungal agent or in the treatment of fungal infections, and a method for manufacturing the composition are also described.

Antiparasitic and/or antifungal composition comprising hydrophobised chitosan

Microparticles and nanoparticles of hydrophobized proteins and an alpha-cyclodextrin, obtained by auto-association in an aqueous medium, the hydrophobized protein being obtained by grafting of alkyl chains coming from fatty acids, by an acylation reaction. These microparticles and nanoparticles constitute systems used for encapsulation of active substances of interest, in particular in the pharmaceutical field, and the vectorization thereof for therapeutic purposes.

Self-associating microparticles and nanoparticles consisting of proteins

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Kawthar Bouchemal