Toyama Chemical Co., Ltd.

Katsuyuki Nagumo

Isamu Saikawa

Shuntaro Takano

Hirokazu Narita

Satoshi Ono

Kaishu Momonoi

Yozo Todo

Tetsuo Yamafuji

Joji Nakano

Yoshinori Konishi

Isao Watanabe

Toru Hiraiwa

Mikako Miyajima

Hideyoshi Nagaki

Isao Kitayama

Hiroyasu Takagi

This invention relates to a process for industrially producing a 1-substituted aryl-1,4-dihydro-4-oxonaphthyridine derivative and a salt thereof which are useful as an antibacterial agent, and also to intermediates therefor and processes for producing the intermediates.

Nicotinic acid derivatives

This invention relates to a novel 1,4-dihydropyridine derivative of the formula ##STR1## wherein R2 is pyridyl, or a salt thereof. These compounds have a vasodilating activity and a platelet aggregation inhibiting activity. Also disclosed are pharmaceutical compositions containing the same.

Pyridyl ester containing 1,4-dihydropyridine derivatives and salts

This invention relates to a 1,4-dihydropyridine derivative of the formula ##STR1## wherein Y represents an oxygen or sulfur atom or a vinylene group, Z represents an oxygen or sulfur atom or an alkylene group, R.sup.2 represents an imidazolyl or pyridyl group and the remaining substituents are herein defined. These compounds have a vasodilating activity and a platelet aggregation inhibiting activity.

Vasodilating and platelet aggregation inhibiting 1,4 dihydropyridines

Process for producing 1-substituted aryl-1,4-dihydro-4-oxonaphthyridine

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Kawasaki, Japan

Katsuyuki Nagumo