Nippon Telegraph and Telephone Corporation

Katsuyoshi Hayashi

Tsutomu Horiuchi

Yuzuru Iwasaki

Nobuaki Matsuura

Emi Tamechika

Suzuyo Inoue

Toru Miura

Hiroshi Nakashima

Shingo Tsukada

Michiko Seyama

Takayuki Ogasawara

Tsuneyuki Haga

Serge Camou

Hisashi Kurasawa

Akinori Fujino

Masumi Yamaguchi

Jyunichi Takahashi

A time-series-data feature extraction device includes: a data processing unit that processes a received unevenly spaced time-series-data group into an evenly spaced time-series-data group including omissions and an omission information group indicating presence or absence of omissions, based on a received input time-series data length and a received minimum observation interval; a model learning unit that learns a weight vector of each layer of a model with a difference between an element not missing in a matrix of the evenly spaced time-series-data group including omissions and an element of an output result of an output layer of the model being taken as an error, and stores the weight vector as a model parameter in a storage unit, the difference being; and a feature extraction unit that receives time-series data of a feature extraction target, calculates a value of the intermediate layer of the model with use of the model parameter stored in the storage unit by inputting the received time-series data of the feature extraction target into the model, and outputs the calculated value of the intermediate layer as a feature that represents temporal changes in data.

Time-series-data feature extraction device, time-series-data feature extraction method and time-series-data feature extraction program

In step S, a specimen containing blood plasma and a coagulation activating agent are introduced into a flow channel, with the coagulation activating agent being positioned ahead, in a state in which portions arrayed in series in the extending direction of the flow channel flow in contact with each other. In step S, in the process in which the coagulation activating agent, the contact region between the coagulation activating agent and the specimen, and the specimen pass through a measurement portion provided midway along the flow channel in the order named, the refractive indices of the coagulation activating agent and the contact region are measured in a time-series manner. In step S, the blood coagulation ability of the specimen is measured by comparing the first refractive index value which is the refractive index of the coagulation activating agent with the second refractive index value which is the minimum refractive index of the contact region.

Blood coagulation test method

A flow cell () includes a plate-shaped bodythat is almost rectangular in a plan view, an introduction portion () that is made of a concave portion formed in the upper surface of the body (), a channel () that is formed inside the body () and has one end connected to the lower end of the introduction portion (), and a delivery portion () that is made of a concave portion formed in the body () and has the lower end connected to the other end of the channel (). The introduction portion () is formed to cause the meniscus of a liquid introduced from an opening to apply, to the liquid, a positive pressure or a negative pressure whose absolute value is smaller than that of a negative pressure applied to the liquid introduced into the channel () by the meniscus of the liquid. The channel () is formed to cause the meniscus of the liquid introduced into the channel () to apply a negative pressure to the liquid. This invention provides a flow cell and a liquid feed system capable of more easily controlling feed of a trace amount of liquid.

Flow cell and liquid feed system

An object of the invention is to provide various flow cells and a method for manufacturing the same, in which formation of a groove on a substrate and formation of components such as an electrode, auxiliary parts such as a pump are not necessary. The inventive flow cells are capable of realize complicated chemical analysis or synthesis or the like. A channel of a porous member provided on a sample-incompatible substrate is formed; the porous member is composed of an air non-contact region having a network structure and an air contact region covering the air non-contact region and having a lower pore density than the air non-contact region; in which a capillary force to be generated within the porous member is a drive force for pumping a liquid.

Flow cell and method for manufacturing the same

Growing community of inventors

Tokyo, Japan

Katsuyoshi Hayashi