Mitsui Toatsu Chemicals, Incorporated

Katsutoshi Ishikawa

Hitoshi Shimotori

Noboru Iida

Tsutomu Ishii

Shuji Ozawa

Toshiaki Kuwatsuka

Masatoshi Gohbara

Yuji Yanase

Hideo Kawashima

Makoto Nishida

Shunichi Inami

Yasunaga Iwasaki

Hiroharu Tanikawa

Takeshi Sekino

Sunao Maeda

Yoshinori Tanaka

Ryuichi Mita

Haruki Mori

Yukihiro Yoshikawa

Shoichiro Ozaki

Seiichi Watanabe

Yoshiro Kanemoto

Sadafumi Koda

Naofumi Tomura

Junya Fujiwara

Toshiyuki Kouno

Yoshimasa Ike

Yuji Yanese

Kazuo Akihiro

Application of a rice blast control agent containing an isothiazolecarboxylic acid derivative of the below-described formula, which shows excellent activity against rice blast (Pyricularia oryzae) in rice cultivation, to the water surface of a paddy rice field results in the absorption of the derivative through roots of rice plants, so that the resistance of the rice plants can be enhanced. ##STR1## wherein R.sup.1 and R.sup.2 independently mean a hydrogen or halogen atom or a particular group, and Y stands for an OR.sub.3 group (R.sup.3 being a hydrogen or alkali metal atom or a particular group), an NHR.sup.4 group (R.sup.4 being a hydrogen atom or a particular group), or a morpholino group.

Isothiazolecarboxylic acid derivatives, rice blast control agents

Pyrimidinyloxy(thio)quinoline derivatives represented by the formula (I) which exhibit an excellent controlling effect for plant diseases and are also safe for crop plants, preparation processes of the derivatives, and agri-horticultural fungicides comprising the derivatives as an active ingredient, are disclosed. ##STR1## In the formula (I), X is an oxygen atom or sulfur atom, Y is a hydrogen atom or halogen atom, Z is a hydrogen atom or methyl, R.sup.1 and R.sup.2 are methoxy or methyl, and n is an integer of 1 or 2.

Pyrimidinyloxy(thio)quinoline derivative, and agri-horticultural

Benzaldehyde acetal compounds represented by the following formula: ##STR1## in which each R is a C.sub.3-8 alkyl group and forms an ether bond with the corresponding oxygen atom of the orthoaldehyde moiety have no injury to crops and, moreover, exhibits superb herbicidal effects owing to the limitation of the number of carbon atoms of each alkyl group to 3-8.

Benzaldehyde acetal compounds, preparation process thereof, and

Process for the preparation of thiazolecarboxylic acid chlorides

Herbicidally active pyridyloxypyrimidines represented by the following formula [I]: ##STR1## wherein R means a formyl group or an acetal group represented by ##STR2## R.sup.1 and R.sup.2 being the same or different and individually denoting an alkyl group having 1-4 carbon atoms or R.sup.1 and R.sup.2 being coupled together and denoting an alkylene group, R.sup.3, having 2-3 carbon atoms; are prepared by reacting 2 formyl-3-hydroxypyridine or 3-hydroxy-2-pyridine carboxaldehyde acetal with 2 halogeno-4,6 dimethoxypyrimidine in the presence of a base.

Pyridyloxypyrimidine derivatives, preparation process thereof, and

Disclosed are dihalogenothiocyanopyrimidine derivatives of the general formula ##STR1## wherein X and Y are halogen atoms, a process for preparing such derivatives, as well as agricultural and horticultural fungicidal compositions containing such a derivative as active ingredient.

Dihalogen-substituted thiocyanopyrimidine derivatives, and agricultural

Disclosed herein are thiocyanopyrimidine derivatives represented by the following general formula: ##STR1## wherein R means an alkyl group having 1-3 carbon atoms and X denotes a halogen atom, their production process, and agricultural and horticultural fungicides containing same as active ingredients. The compounds of this invention can provide ideal agricultural and horticultural fungicides, since they exhibit outstanding fungicidal activities against plant pathogens led by late blight and downy mildew, their toxicity to animals are low and they are not phytotoxic. The compounds of this invention can be obtained by reacting pyrimidine derivatives represented by the following general formula: ##STR2## with thiocyanates while using an organic acid as a solvent. Good results can be obtained particularly when formic acid is used as a solvent.

Production process for thiocyanopyrimidine

Thiocyanopyrimidine, agricultural and horticultural fungicide containing

Disclosed herein are a novel compound, 5-methylthiopyrimidine derivative, notably that represented by the following general formula: ##STR1## wherein X means an oxygen or sulfur atom and R.sup.2 denotes a methyl, allyl or propargyl group, its preparation process and an agricultural and horticultural fungicide containing same as an active ingredient. The above compound exhibits outstanding control effects against plant diseases, especially, late blight of potatoes and the like and downly mildew. It permits preparation of an ideal agricultural and horticultural fungicide owing to its very low toxicity against mammal and fish and its no phytotoxicity.

5-Methylthiopyrimidine derivatives, their preparation process and

New uracil derivatives of the general formula: ##STR1## wherein R.sup.1 stands for a hydrogen atom or a grouping of the formula: ##STR2## R.sup.2 for a hydrogen atom, an alkyl group or a phenyl group and R.sup.3 for an alkyl group or a phenyl group, with the proviso that when both R.sup.1 and R.sup.2 stand for a hydrogen atom, R.sup.3 stands for a phenyl group or a straight chain alkyl group with 3.about.11 carbon atoms, that when R.sup.1 stands for a hydrogen atom and R.sup.2 for methyl group, R.sup.3 stands for an alkyl group with at least 2 carbon atoms or a phenyl group, and that when R.sup.1 stands for a hydrogen atom and R.sup.3 for methyl group, R.sup.2 stands for an alkyl group with at least 2 carbon atoms or a phenyl group. These uracil derivatives are prepared by reacting 5-fluorouracil with an .alpha.-haloalkyl carboxylate or with an aldehyde diacylate or by hydrolyzing a 1,3-bis(acyloxymethyl)-5-fluorouracil with an acid or alkali. These uracil derivatives are useful as improved anti-tumor agents especially for oral administration and injection.

Uracil derivatives

Growing community of inventors

Mobara, Japan

Katsutoshi Ishikawa