Shibuya Corporation

Katsuki Hashimoto

Tetsuya Nishimura

Kazuhito Tanimoto

Soma Watanabe

Yusuke Hirosawa

Masaomi Shioya

In an aeration method for an isolator system, an incubator is connected to an isolator through a chamber. After closing a door at each sidewall of the chamber, a decontaminating gas is supplied to the chamber through gas supply passages to decontaminate the inside thereof. Next, air is supplied into the chamber through the gas supply passages and an initial aeration is carried out by discharging the decontamination gas through a gas discharge passage. Then, after a door between the isolator and the chamber is opened, and blowers are stopped, gas at a positive pressure in the isolator is introduced into the chamber. The decontaminating gas in the chamber is rapidly discharged to an outside through the gas supply passages and the gas discharge passage, and aeration in the chamber is completed. The time required for aeration of the chamber can be drastically reduced as compared with conventional aeration processes.

Aeration method of isolator system

An isolator systemincludes: a main isolatorin which an aseptic state is maintained and which is for performing an aseptic operation; an incubatorin which the aseptic state is maintained and which is connected to the main isolatorand is for culturing cells and the like; decontamination meansfor decontaminating the inside of the main isolator; and a decontamination stationthat decontaminates the inside of the incubator. The isolator systemfurther includes a blocking memberfor sealing a connection portfrom the outside, the port being provided in the main isolatorand being for connection with the incubator. When the inside of the main isolatoris decontaminated, the connection portis sealed from the outside with the blocking member. The isolator system that can efficiently decontaminate the main isolator and the subisolator connected to this main isolator can be provided.

Isolator system and decontamination method therefor

An incubatorincludes a cultivating chamberfor cultivating culture in a plurality of containersand a supply deviceprovided outside the cultivating chamberand supplying steam into the cultivating chamberfor humidification. The supply deviceincludes a supply chamberA in which a trayfor reserving water is accommodated and an ultrasonic atomizing devicefor atomizing water. The water in the trayis easily made into steam by the ultrasonic atomizing device, passes through an HEPA filterprovided in an opening portionB and is supplied into the circulation passageof the cultivating chamber

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Kanazawa, Japan

Katsuki Hashimoto