The Secretary of State for Environment, Food and Rural Affairs

Isis Innovation Limited

The Secretary of State for Environment, Food & Rural Affairs, Acting Through the Animal Health and Veterinary Laboratories Agency

Katie Ewer

Neil Graham Stoker

Benjamin Sidders

Hans Martin Vordermeier

Ajit Lalvani

Hanns Martin Vordermeier

There is provided a diagnostic reagent for use in the detection oforinfection in an animal, comprising a peptide which has an epitope fromhypothetic protein Mb3645c (SEQ ID NO: 1) or an epitope from a polypeptide having at least 76% identity with SEQ ID NO: 1.

antigens

Mycobacterium antigens

[object Object]

Method of diagnosing in an individual recent exposure to an agent which is a pathogen, vaccine or any other moiety which induces a cellular response, said method comprising determining in vitro whether the T cells of the individual recognise a protein from said agent having a length of at least 30 amino acids, to a greater extent than one or more peptide epitopes from the agent, a greater extent of recognition of the protein indicating that the individual has recently been exposed to the agent.

Diagnostics method

Growing community of inventors

Oxford, United Kingdom

Katie Ewer