Pfizer Hospital Products Group, Inc.

Howmedica Osteonics Corporation

Stryker Technologies Corporation

Inco Alloys International, Inc.

Kathy K Wang

Larry J Gustavson

John H Dumbleton

Michael Meehan

Nicholas Nai Guang Dong

Mark L Robinson

Nicholas Nai Dong

The invention relates to implantable medical devices, particularly, to porous structures for such devices. In one aspect, the invention provides a porous metal scaffold comprising a porous metal network having pores defined by metal webs, the metal webs covered with at least one layer of metal particles bonded to the metal webs. In other aspects, the invention provides methods of forming porous scaffolds. In one such aspect, the method includes providing a polymer foam; forming a skin of biocompatible metal on the polymer foam by low temperature arc vapor deposition; and heating the polymer foam and the metal skin above the decomposition temperature of the polymer foam in an inert gas atmosphere; thereby the polymer foam decomposes producing a green metal foam. In yet other aspects, the invention provides methods of improving stability of porous scaffolds.

Porous metallic scaffold for tissue ingrowth

Orthopaedic wires, cables, and methods of making them are based on the discovery that, in clinical orthopaedic applications, material toughness and fatigue strength are as important or more important than ultimate tensile strength. The wires and cables of the invention have a tensile strength lower than 280 ksi, but higher than 175 ksi. The presently preferred wires and cables have a tensile strength of 210-240 ksi. The fatigue strength of the wires and cables of the invention is between six and ten times that of other high strength cables used in orthopaedic applications. One method of making the wires and cables includes annealing high tensile strength wire or cable to reduce its tensile strength and thereby increase its fatigue strength. Another method is to cold work fully annealed wire or cable to the extent of decreasing its cross section by approximately 18%. Presently preferred wires and cables according to the invention are made from chromium-cobalt alloy, preferably wrought VITALLIUM (registered trademark) alloy.

Orthopaedic wires and cables and methods of making same

Method for preparing a high strength, low modulus, ductile, biocompatible titanium base alloy containing one or more isomorphous beta stabilizers, eutectoid beta stabilizers and optional alpha stabilizers, characterized by a modulus of elasticity not exceeding 100 GPa; comprising blending pre-selected amounts of the alloying ingredients, melting the blend in a plasma arc furnace, allowing the melt to cool and solidify, vaccum arc remelting and thermomechanically processing the resulting solid to provide the desired alloy.

Method of making high strength, low modulus, ductile, biocompatible

A high strength, low modulus, ductile, biocompatible titanium base alloy containing one or more isomorphous beta stabilizers, eutectoid beta stabilizers and optional alpha stabilizers, characterized by a modulus of elasticity not exceeding 100 GPa; a method for the preparation of said alloy and prostheses made from said alloy.

High strength, low modulus, ductile, biopcompatible titanium alloy

A dispersion strengthened cobalt-chromium-molybdenum alloy produced by gas atomization containing a fine oxide dispersion, and characterized, after fabrication by gas atomization, thermomechanical processing and further high temperature exposure, by excellent corrosion resistance, high fatigue strength, high ductility and high temperature stability; a process for producing said alloy and prostheses formed from said alloy.

Prosthesis formed from dispersion strengthened

Dispersion strengthened cobalt-chromium-molybdenum alloy produced by gas

An alloy made by water atomizing the charge component into powder, extruding the powder, hot rolling the powder and heat treating the product. The alloy displays superior stress rupture characteristics when compared to a corresponding conventionally wrought alloy.

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Suffern, NY, United States of America

Kathy K Wang