Hologic, Inc.

Cytyc Corporation

Kathy K Mui

David J Zahniser

Kam Lin Wong

Jim Linder

Ellen E Sheets

Howard B Kaufman

James R Linder

Components, e.g., background, cytoplasm, nucleus and nucleolus, of a biological specimen are identified using multi-wavelength analysis. Specimen components, such as nucleoli, are selected, and a determination is made whether cells having nucleoli are cancer cells or regular repair cells based on one or more physical characteristics of the identified component. The physical characteristics can be one or more of a shape, size, texture and gray value.

Method and system for processing an image of a biological specimen

Methods, systems and computer readable media for processing one or more biological specimens carried by specimen slides. Images of objects in a specimen are acquired and objects of interest in the acquired images are identified. Additional images of identified objects of interest may be acquired at multiple wavelengths. Cellular features of objects of interest are extracted from images and may be used for classifying the specimen, e.g., as normal or suspicious/abnormal, based a probabilistic model that utilizes the extracted features.

Methods and systems for processing biological specimens utilizing multiple wavelengths

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Chelmsford, MA, United States of America

Kathy K Mui