University of Texas System

William Marsh Rice University

Leland Stanford Junior University

Kathy A Mason

James Mitchell Tour

Dmitry Kosynkin

S Ward Casscells

Ashley Leonard

Jared L Hudson

Luka Milas

Jeffrey N Myers

Valerie C Moore

Brandi Katherine Price

Rebecca Lucente-Schultz

Zvonimir L Milas

Cullen Taniguchi

Jodie L Conyers, Jr

The disclosure relates to the treatment of primary and metastatic cancer using radiation. Specifically, the disclosure relates to methods providing for the selective accretion of cytoprotective agent in tissues and/or organs, sensitive to radiation that are adjacent to malignant tumors prior to radiation of the tumors at a dose that otherwise would be toxic to the tissues and/or organs, but are necessary to achieve ablative outcome on the tumors.

Selective accretion of cytoprotectant in radiation-sensitive tissues and uses thereof

Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described.

Water-soluble carbon nanotube compositions for drug delivery and medicinal applications

Growing community of inventors

Houston, TX, United States of America

Kathy A Mason