Baxter Aktiengesellschaft

Baxter Innovations Gmbh

Kathrin Thomas-Urban

Johann J Eibl

Friedrich Dorner

Bernhard Fischer

Artur Mitterer

&Ouml;yvind L Sch&ouml;nberger

Oyvind L Schönberger

Öyvind L Schönberger

There is disclosed a method of recovering factor VIII/vWF-complex which is characterized in that factor VIII/vWF-complex from a protein solution is bound to a cation exchanger and is recovered by step-wise elution of factor VIII/vWF-complex, which particularly contains high-molecular vWF multimers, as well as a factor VIII/vWF-complex obtainable by means of cation exchange chromatography.

Factor VIII/vWF-complex and methods of purifying same

Factor VIII/vWF complexes and compositions

Methods for recovering factor VIII/vWF-complex that involve binding factor VIII/vWF-complex from a protein solution to a cation exchanger and recovering factor VIII/vWF-complex by step-wise elution are disclosed. The recovered complex contains high-molecular vWF multimers. Compositions containing factor VIII/vWF-complex as purified by cation exchange chromatography are also provided.

Method for purifying factor VIII/vWF company by cation-exchange chromatography

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Freiburg, Germany

Kathrin Thomas-Urban