Apse, Inc.

Kathleen B Hall

Juan Pedro Arhancet

Juan Pedro Humberto Arhancet

Neena Summers

Kimberly Delaney

Edward Oates

Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNAs and shRNAs, miRNAs, messenger RNAs, small peptides and bioactive molecules.

Compositions and methods using capsids resistant to hydrolases

Processes and compositions to produce, package, and purify virus like particles containing heterologous cargo molecules utilizing self assembling proteins and protease treatment coupled with simple precipitation and filtration methods are described.

Growing community of inventors

St. Louis, MO, United States of America

Kathleen B Hall