Idexx Laboratories, Inc.

Katherine Jean Esty

Thomas Patrick O'Connor, Jr

Charles R Carpenter

Ramaswamy Chandrashekar

Ali Naqui

Chun-Ming Chen

Haoyi Gu

Gary Madsen

The present invention provides devices and methods for determining the presence or absence of pathogens in a biological sample and for the concurrent determination of the antimicrobial susceptibility of pathogens present. The devices and methods of the present invention are able to make the determinations without pre-selection of target bacteria. Instead, all organisms from the sample are applied to the device. In wells where one or more antimicrobial agents are present only pathogens resistant to the antimicrobial agent grow. This allows the user to determine the presence of target pathogens and concurrently determine the resistance patterns of the organisms without the need to subculture the organisms. The present invention also provides methods of performing a business service of performing the determinations described above, and kits containing the devices and descriptions of the methods.

Methods and devices for the detection of pathogenic microorganisms and their antimicrobial susceptibility

A method and device for detecting a West Nile Virus (WNV) infection including contacting a biological sample from a subject with an anti-IgM antibody and a recombinant WNV E polypeptide and detecting whether the polypeptide substantially binds to an antibody in the sample. The invention also includes a method and device for determining whether an animal is infected with West Nile Virus (WNV), or is either not infected or is vaccinated with a WNV vaccine.

Detection of West Nile Virus

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Westbrook, ME, United States of America

Katherine Jean Esty