Modern Meadow, Inc.

Katherine Amy Congdon

Brendan Patrick Purcell

Lixin Dai

Stephen M Spinella

David Thomas Williamson

Darryl Miles Cassingham

Suzanne Lee

Chi Man Ng

Hemanthram Varadaraju

Morgan Schneider

Sarah Schachtschneider

Callie McBride Clayton

A biofabricated material comprising a network of crosslinked collagen fibrils produced from recombinant collagen that contains substantially no 3-hydroxyproline residues is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side (e.g., distal surface) to the other (proximal inner layers).

Biofabricated material containing collagen fibrils

The invention herein provides biofabricated materials having zonal properties and methods of making biofabricated materials having zonal properties.

Biofabricated leather articles having zonal properties

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Suffolk, United Kingdom

Katherine Amy Congdon