Boehringer Ingelheim Vetmedica Gmbh

Katharina Hedwig Toepfer

Axel Lischewski

Jeffrey P Knittel

Veljko Nikolin

Alexander Brix

Konrad Stadler

Amanda Brown

Francois-Xavier Orveillon

Michael Johannes Gassel

Kathy Schlesinger

Elida Bautista

Matthew Coons

Leigh Wilmes

The present invention in particular relates to a method of producing an immunogenic composition exhibiting reduced virucidal activity, as well as to the immunogenic composition and uses thereof, wherein the method in particular comprises the steps of: (a) providing a mixture with a first liquid and a recombinant protein, (b) concentrating the recombinant protein in the mixture by removing a portion of the first liquid from the mixture, and (c) processing the solution resulting from step (b) by continuous diafiltration.

Method of producing an immunogenic composition

The present invention relates to the field of vaccines and medicaments for the prophylaxis and treatment of infectious diseases in ruminants. In particular, it relates to inactivated Schmallenberg virus (SBV) useful as vaccine or medicament for preventing or treating viremia, the transmission and clinical symptoms, in particular malformations in newborn ruminants such as cattle, sheep and goats, induced by SBV.

Schmallenberg virus (SBV) vaccine, methods of production, and uses thereof

Growing community of inventors

Hannover, Germany

Katharina Hedwig Toepfer