Contipro A.s.

Ceske Vysoke Uceni Technicke V Praze, Fakulta Strojni

Ustav Struktury a Mechaniky Hornin Av Cr, V.v.i.

Prospon Spol. S.r.o.

Katerina Knotkova

Tomas Suchy

Vladimir Velebny

Radovan Buffa

Ivana Basarabova

Josef Chmelar

Jaromir Kulhanek

Helena Krejci

Lubos Sobotka

Hana Vagnerova

Marek Pokorny

Martina Hermannova

Jaroslav Novotny

Drahomira Chladkova

Jan Klemes

Lucie Marholdova

Michaela Moravkova

Kristyna Lipenska

Martin Fogl

Stanislav Pepeliaev

Tomás Pitucha

Martin Sojka

Marek Pokorný

Veronika Stepankova

Adela Kotzianova

Vit Svozil

Rastislav Ballay

Margit Zaloudkova

Zdenek Cejka

Lukas Horny

Jana Ruzickova

Eva Soukupova

Tomas Pitucha

Frantisek Denk

Monika Supova

Zbynek Sucharda

Sarka Ryglova

A chlorinated derivative of hyaluronic acid or of a modified hyaluronic acid (chloramide) is provided. The chloramide has an amidic group (&#x2014;NH&#x2014;CO&#x2014;). The hydrogen of the amidic group is substituted by a chlorine atom, according to the structural formula &#x2014;NCl&#x2014;CO&#x2014;. The substitution degree of the hyaluronic acid or of the modified hyaluronic acid by chlorine is in an amount of from 50 to 100 %.

Chlorinated derivative of hyaluronic acid, method of preparation thereof, a composition containing the derivative, and use thereof

An antimicrobial composition is provided. The composition comprises a chloramid of hyaluronic acid or of modified hyaluronic acid. The chloramid has an amidic group (&#x2014;NH&#x2014;CO&#x2014;). The hydrogens of the amidic group are substituted by chlorine atoms according to the structural formula &#x2014;NCl&#x2014;CO&#x2014;. The composition further comprises an iodide. The substitution degree of the hyaluronic acid or of the modified hyaluronic acid by chlorine is in an amount of from 50% to 100%.

Composition comprising an iodide and a derivative of hyaluronic acid with an oxidative effect, method of preparation thereof and use thereof

Device for the production of nanofibrous and/or microfibrous layers having an increased thickness uniformity by spinning a liquid material (), said device comprising: a collecting electrode (), a spinning nozzle () for dispensing the liquid material () to be spun, an assembly for guiding the collecting electrode () and/or for guiding a base strip () along the collecting electrode () or adjacent to it, such that&#x2014;in the area faced by the outlet orifice () of the spinning nozzle ()&#x2014;the collecting electrode () and/or the base strip () move(s) in the direction (MD) spaced from the outlet orifice () of the spinning nozzle (), a power supply for generating a voltage of 10 to 150 kV between the collecting electrode () and the spinning nozzle (), at least one body (), which moves along the liquid surface to destabilize the locations of the points where fibres () are formed on the surface of the liquid material () at the outlet orifice () of the spinning nozzle (). The nanofibrous and/or microfibrous layers having an increased thickness uniformity are produced by spinning a liquid material () in an electrostatic field, wherein a body () is moved along the surface of the spun liquid in order to destabilize positions of locations, where the fibers originate.

Device and method for production of nanofibrous and/or microfibrous layers having an increased thickness uniformity

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Chocen, Czechia

Katerina Knotkova