Edwards Lifesciences Corporation

Mitralign, Inc.

Sirtex Medical Limited

Kate E Cutuli

Nareak Douk

Michael W Sutherland

Morgan House

Richard J Morrill

Jonathan L Goodwin

Matt Guimond

Paul A Spence

Jason Robinson

Mark A Maguire

Edward I McNamara

Joseph P Lane

Hiroatsu Sugimoto

Steven D Cahalane

Aaron M Call

Donald S Baim

Christopher Lee

Justin McCarthy

Christopher C Lee

Chirstopher Lee

Joshua Rose

Diana Sulas Thompson

Jonathan Goodwin

Charlotte A Gallagher

Patrick T Thrailkill

A catheter system including a wire, a translatable catheter, and first and second tethers is introduced into a body of a subject. The translatable catheter has a curved portion proximate a distal end of the translatable catheter. The first tether is coupled to the wire, and passes proximally through the translatable catheter. The second tether is attached to the curved portion. The catheter system is positioned such that the wire is disposed at a first location in the body. While the wire remains at the first location, the translatable catheter is translated away from the wire by manipulating the first tether and the second tether. Other embodiments are also described.

Translation catheters, systems, and methods of use thereof

Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

Tissue anchors, systems and methods, and devices

The present teachings generally relate to translation catheter systems and method of using thereof in treating defective mitral valves. Specifically, a translation catheter system includes a catheter configured to move substantially laterally along the mitral annulus and the lateral movement of the catheter is substantially continuous and substantially adjustable. Accordingly, a method of using such a translation catheter includes advancing a first wire across the mitral annulus at a first treatment location, delivering a catheter at or near the first treatment location, moving the catheter substantially laterally to a second treatment location, and advancing a second wire across the mitral annulus, where the distance between the first and second treatment locations is substantially adjustable and optionally visualized.

Translation catheters and systems

Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty. One of the methods includes positioning at least two discrete, flat first anchor elements along a first side of a tissue of the mitral valve annulus in stacked relationship and at least two other discrete, flat first anchor elements along the second side of the tissue of the mitral valve annulus in stacked relationship.

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Salem, NH, United States of America

Kate E Cutuli