Richter Gedeon Vegyeszeti Gyar Rt

Katalin Pik

Endre Csanyi

Jozsef Borsi

Erzsebet Mago Nee Karacsony

Lajos Wolf

New compounds of the formula ##STR1## wherein R is hydrogen or methyl group,

Compounds with ergoline skeleton

New compounds of the general formula (I) ##STR1## wherein R stands for hydrogen or methyl group, x y stands for a group of the formula ##STR2## and R.sub.1 stands for a group of the formula (III), (IV) or (V) ##STR3## wherein n is an integer from 4 to 10, ARE PREPARED BY ACYLATING A COMPOUND OF THE GENERAL FORMULA (II), ##STR4## wherein R and x y each have the same meanings as defined above, and R.sub.2 stands for a group of the formula (VI), (VII) or (VIII), ##STR5## with a C.sub.6-12 carboxylic acid or a C.sub.6-12 carboxylic acid halide. The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.

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Budapest, Hungary

Katalin Pik