Abbott Diagnostics Scarborough, Inc.

Alere San Diego, Inc.

Karthikeyan Kumaravadivelu

Olaf Piepenburg

Justin Davidson

Catherine Jean Greenwood

Oliver Nentwich

Maulik Vinod Patel

Austin Matthew Derfus

Alexander Schenk Zu Schweinsberg

Richard B Roth

Austin Derfus

Adrian P Crute

Timothy L Higby

Aric Joneja

Torsten Gliewe

Neil Quitoviera

Aspects of the present disclosure include sample preparation cartridges including a cylindrical structure and one or more covers. The cylindrical structure further includes a top, a bottom, an annular wall, a plurality of cavities in the annular wall that form a plurality of open-sided chambers on the annular wall and one or more interconnections providing fluidic communication between the plurality of chambers. The one or more covers cover the open side of the plurality of chambers. Also provided is a cylinder housing comprising one or more magnets. The sample preparation cartridge is removably disposed into the cylinder housing or adjacent to the cylinder housing. Methods of using the sample preparation device are also provided.

Sample preparation device and methods for using same

A microfluidic device includes an inlet port configured to receive a sample, a first reaction chamber fluidically coupled to the inlet port, a first pump fluidically coupled to the inlet port, a second pump fluidically coupled to a mixing chamber, a metering channel fluidically coupled to the first reaction chamber and to the mixing chamber, and one or more second reaction chambers fluidically coupled to the mixing chamber. The first pump is configured to move fluid from the inlet port to the first reaction chamber and from the first pump to the inlet port. The second pump is configured to move fluid from the second pump to the mixing chamber, from the first reaction chamber to the mixing chamber, and from the mixing chamber to the one or more second reaction chambers.

Microfluidic devices and related methods

Growing community of inventors

San Diego, CA, United States of America

Karthikeyan Kumaravadivelu