Taro Pharmaceuticals Inc.

Karthikeyan Iyanar

Curtis Harwig

Jeremy D Pettigrew

Jeyaprakashnarayanan Seenisamy

Mahesh Narayan Keregadde

Jennifer Cross

Samir Satish Kher

Compounds of formula (1): wherein, R, R, R, R, Rand Rare described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable salt or solvate thereof, are described herein, as well as other compounds. These compounds are useful in treating inflammation and/or pain. Compositions comprising a compound of the invention are also disclosed, as are methods of using the compounds to treat inflammation and/or pain.

Indene derivatives useful in treating pain and inflammation

Compounds of formula (I): wherein, R, R, R, R, Rand Rare described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable salt or solvate thereof, are described herein, as well as other compounds. These compounds are useful in treating inflammation and/or pain. Compositions comprising a compound of the invention are also disclosed, as are methods of using the compounds to treat inflammation and/or pain. 

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Vancouver, Canada

Karthikeyan Iyanar