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Unchained Labs

Rap.id Particle Systems Gmbh

Karsten Goede

Markus Lankers

Oliver Valet

Lothar Holz

Steve Bober

Lisa Krapf

The invention relates to a liquid cell () for the microscopic image capture and Raman spectroscopic material analysis of a particle suspension in a reflected light microscope, having at least the following components: a measuring chamber () which has a base (), a measuring window () opposite the base (), and a seal (), wherein the base () has a planar design at least in one region of the support of the seal (), and the base () has a reflective surface () which is provided such that Raman excitation light incident through the measuring window () is reflected on the reflective surface () in a directed manner such that the background signal in a Raman measurement is reduced and the Raman signal of a particle in a suspension is increased. The invention further relates to a microscope which has such a liquid cell.

Liquid cell for the microscopic imaging and Raman spectroscopic material analysis of particles suspensions

Disclosed herein is a system, particularly a microscope system, for confocal Raman-spectroscopic measurements. The system is configured to detect minute sample amounts of microbes in a sample chamber with a lid, wherein the system is configured such that a comparably large working distance between the objective lens and the sample is sustained such that a measurement can be performed through the lid of the sample chamber. This allows for cultivating and measuring the sample in the same container.

System and method for confocal raman-spectroscopic measurements of biological samples

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Berlin, Germany

Karsten Goede