Evotec Ag

Evotec Oai Ag

Universität Osnabrück

Ionovation Gmbh

Karsten Gall

Stefan Jäger

Werner Stürmer

Silke Hinnah

Dagmar Lambrü

Sonja Dröge

Michaela Schäfer

Peet Kask

Kaupo Palo

Christian Eggeling

Rolf Guenther

Helmut Rosemeyer

Edith Malecki

Leif Brand

Ülo Mets

Claus Seidel

Sergei Korneev

Emma Werz

Richard Wagner

Andreas Wirth

Martin Klumpp

Werner c/o Altana Pharma Ag Stürmer

Silke Christine Hinnah

Michaela c/o Altana Pharma Ag Schäfer

The present invention relates to a method for detecting an analyte in a sample comprising the steps of

Method for detecting an analyte in a sample

The present invention relates to a method for detecting analytes in a sample comprising the steps of

Method for detecting analytes in a sample

A device for the measurement of chemical and/or biological samples, in particular by means of luminescence spectroscopy, comprises an irradiation unit, a sample receiver, at least one optical unit and a detector unit. The color marker in the sample, which contains at least one color marker, is stimulated by irradiation into producing luminescence and gives off light. The light emitted by the color markers is detected by detectors in the detector unit. According to the invention, the measurement results may be improved by the irradiation unit generating pulsed irradiation. The irradiation unit is thus preferably controlled by a control unit in such a way that the irradiation pulses impinge on the sample in a temporal sequence.

Method and device for the measurement of chemical and/or biological samples

A method for distinguishing samples having flourescent particles includes (a) monitoring intensity fluctuations of fluorescence emitted by the particles in at least one measurement volume by detecting sequences of photon counts by at least one photon detector, (b) determining, from the sequences of photon counts, intermediate statistical data involving at least two probability functions of the number of photon counts detected in different sets of counting time intervals, and (c) determining from the intermediate statistical data a distribution of particles as a function of at least two arguments, wherein one argument is a specific brightness of the particles, or a measure thereof, and another argument is a diffusion coefficient of the particles, or a measure thereof.

Fluorescence intensity multiple distributions analysis: concurrent determination of diffusion times and molecular brightness

Growing community of inventors

Lunestedt, Germany

Karsten Gall