Thomas Helledays Stiftelse for Medicinsk Forskning

Karl Vallin

Thomas Helleday

Evert Homan

Martin Scobie

Martin Haraldsson

Martin Henriksson

Lars Sandberg

Sanjay Borhade

Cynthia Paulin

Pål Stenmark

Christoffer Bengtsson

Pal Stenmark

A compound of formula I or a pharmaceutically acceptable salt thereof. The compound is useful in therapy, e.g. for the treatment of cancers, inflammation, autoimmune diseases and graft-versus host diseases (e.g. in transplantation patients). A pharmaceutical composition comprising the compound or its salt and a method for preparing the compound.

2,6-diamino-3,4-dihydropyrimidin-4-one derivatives and use thereof in therapy

A compound of formula (I) or a pharmaceutically acceptable salt thereof. The compound is useful in therapy, e.g. for the treatment of cancers, inflammation, autoimmune diseases and graft-versus host diseases (e.g. in transplantation patients). A pharmaceutical composition comprising the compound or its salt and a method for preparing the compound. 

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Stockholm, Sweden

Karl Vallin