Hoechst Aktiengesellschaft

Karl Sturm

Roman Muschaweck

Max Hropot

Franz Starey

What are disclosed are salidiuretic compounds of the formula ##STR1## and physiologically acceptable salts thereof, wherein R is phenyl, furyl or thienyl, intermediates of said compounds, methods for making said compounds, salidiuretic pharmaceutical preparations containing said compounds or salts, and methods for treating humans and other mammals with such compounds or salts.

5-Phenyltetrazoles and their use as salidiuretics

The invention relates to base-substituted anthranilic acids of the formula I ##STR1## in which R denotes furyl, thienyl or phenyl, and to physiologically acceptable salts thereof, and also to a process for their preparation, to an agent containing these and to their use as medicaments.

Base-substituted anthranilic acids, a process for their preparation and

The present invention relates to compounds of the formula I ##STR1## wherein R is furyl, thienyl or phenyl, to physiologically acceptable salts thereof, to a process for their manufacture, to a composition comprising said compounds and to their use as a medicament.

2,4-Diamino-5-sulfamoylbenzene sulfonic acids and process for their

What are disclosed are compounds of the formula ##STR1## in which R denotes alkyl, alkenyl, cycloalkyl or cycloalkylalkyl, each of which has up to 10 C atoms, or phenyl and Ar denotes phenyl, thienyl or furyl and salts thereof, the preparation of these compounds and their use as medicaments and also medicaments of this type as such.

5-Sulfamoyl-orthanilic acids, processes for their preparation and their

Salidiuretically-active 5-Sulfamoyl-orthanilic acids and their salts, substituted in 4-position by halogen, methyl, phenoxy or phenylthio and by furyl or thienyl at the nitrogen atom, are disclosed, as is and a process for their manufacture by reacting a furyl- or thienyl-substituted amine with corresponding halogen-substituted benzene derivatives.

5-Sulfamoyl-orthanilic acids and process for their preparation

Antihypertensively-active 3-sulfamoyl-4-piperazinyl-benzoic acids, optionally substituted in the 2-position by halogen or alkyl, and the esters, amides, and nitriles of these acids are disclosed, as is a method for making these compounds by the reaction of the corresponding 4-halogeno- or 4-alkyl-(or 4-aryl-) sulfonyloxy-benzoic acids (or their esters etc.) with piperazines.

Basically substituted 3-sulfamoylbenzoic acid derivatives and process

A process for the manufacture of sulfamoyl anthranilic acids of the general formula I ##STR1## in which Ph is phenyl substituted with 1 or 2 halogen atoms, alkyl groups or etherified hydroxy groups, and R is aralkyl, heteroaralkyl or cycloalkyl-alkyl, unsaturated in the aliphatic moiety, including oxygen or sulfur and/or substituted with halogen, alkyl or alkoxy in the aromatic moiety, by reacting carboxylic acids with at least one mol-equivalent of an amine

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Heidesheim, Germany

Karl Sturm