Hoechst Aktiengesellschaft

Karl Muth

Rudi Weyer

Walter Aumuller

Helmut Weber

Volker Hitzel

Felix Helmut Schmidt

Ruth Heerdt

Erich Haack

A benzene-sulfonyl semicarbazide of the formula ##STR1## wherein R is such as phenyl and substituted phenyl, cyclohexyl or alkyl, Y is -CH.sub.2 CH.sub.2 - or ##STR2## is alkylene-imino of 3 to carbon atoms which may also be substituted; a representative compound is 4-[4-(.beta.-&lt;2-methoxy-5-chloro-benzamido-&gt;-ethyl)-benzene-sulfonyl]-1,1- (.gamma.,.gamma.-dimethyl-pentamethylene)-semicarbazide.

Benzene-sulfonyl semicarbazides and process for preparing them

Benzenesulfonyl-ureas of the formula ##STR1## wherein X represents ##STR2## IN WHICH Z represents hydrogen, halogen, a trifluormethyl group, an alkyl or an alkoxyl radical in 4- or 5-position, or ##STR3## Y represents --CH.sub.2 --CH.sub.2 --, --CH--(CH.sub.3)--CH.sub.2 --or --CH.sub.2 --CH--(CH.sub.3)--, R represents a radical of

Benzenesulfonyl-ureas and process for preparing them

Sulfonyl-ureas of the formula X--CO--NH--A--SO.sub.2 --NH--CO--NH--R.sup.1, in which R.sup.1 represents cyclopentylmethyl, alkyl-cyclopentylmethyl or dialkyl-cyclopentylmethyl, having up to 2 carbon atoms in the alkyl rest, or cyclopentylethyl, X represents a. ##SPC1## In which R.sup.2 represents hydrogen, F, Cl, Br, CF.sub.3, CH.sub.3 or OCH.sub.3, b. ##SPC2## In which R.sup.3 represents hydrogen, Cl or CH.sub.3, c. ##SPC3## In which R.sup.4 represents hydrogen, Cl or Br, A represents one of the groupings ##SPC4## And their physiologically tolerated salts, process for preparing them and pharmaceutical preparations containing them.

Substituted quinoline-8-carboxamido ethyl benzene-sulfonyl

Benzene sulfonyl ureas of the formula ##SPC1## In which

Benzene sulfonyl ureas

Benzenesulfonyl-ureas having hypoglycemic activity and corresponding to the formula ##SPC1## Wherein R.sup.1 is

Benzenesulfonyl ureas

N-[4-(.beta.-&lt;2-methoxy-5-chloro-benzamido&gt;-ethyl)-benzenesulfonyl]-N'-cycl opentyl-urea of the formula ##SPC1## Having a long-lasting and strong hypoglycemic action in the treatment of diabetes mellitus and a process for its manufacture.

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Kelkheim (Taunus), Germany

Karl Muth