Sanofi

Karl Hewson

Tom Oakley

Stuart Milne

Mark Pawulski

Ben Kubler

Adam Jonathan Frederick Stops

Medical syringe

The invention refers to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises at least one clicker mechanism () for generating a haptic and/or audible feedback during dose selecting, wherein the clicker mechanism () generates a different feed-back when selecting single units or multiples of single units.

Drug delivery device

The invention refers to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing (), a cartridge () containing a medicament and a last dose protection mechanism for preventing the selection of a dose, which exceeds the amount of medicament left in a cartridge (). This last dose protection mechanism comprises a first member (), which is rotatable in a first direction during dose selecting and in the opposite direction during dose dispensing, a second member () coupled to the first member () and to the housing () such that the second member is moved relative to the first member () and to the housing () upon rotation of the first member () and a third member () which is moved relative to the first and second member () during dose dispensing. Abutment of the second and third member () prevents increasing the selected dose.

The invention relates to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a dosing element (), which rotates in a first direction during dose selecting and rotates in a second, opposite direction during dose dispensing, and a display () for indicating the selected dose. The display () comprises at least one belt () having symbols for indicating the selected dose and being coupled to the dosing element () such that a rotation of the dosing element () spools the belt ().

A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a dose limiter for preventing the setting of a dose, which exceeds the amount of liquid left in a cartridge of the drug delivery device. The device includes a cartridge containing liquid, a dosing element, which rotates during dose selecting, a last dose nut coupled to the dosing element during dose selecting such that rotation of the dosing element causes an axial movement of the last dose nut, and a stop element, which is provided on the dosing element and which blocks further movement of the last dose nut, if a dose is selected corresponding to the amount of liquid left in the cartridge. The device further includes a last dose sleeve rotationally coupled to the dosing element during dose selecting and rotationally decoupled from the dosing element during dose dispensing.

A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a dose limiter for preventing the setting of a dose exceeding an amount of liquid left in a cartridge of the drug delivery device. The device includes a housing, a dose selector for selecting a dose by rotation relative to the housing, a dosing element, and a releasable clutch for rotationally coupling the dosing element to the dose selector during dose selecting and for rotationally decoupling the dosing element from the dose selector during dose dispensing. The clutch includes a male spline, a corresponding female spline and a curved or inclined surface which is orientated such that re-engagement of the clutch guides the male spline into a predefined rotational orientation with respect to the female spline.

A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing, a cartridge holder for receiving a cartridge, a lead screw and means for driving the lead screw during dose dispensing. The lead screw is coupled to the cartridge holder such that the cartridge holder is axially displaced with respect to the housing and the lead screw during dose dispensing.

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Cambridge, United Kingdom

Karl Hewson