Behringwerke Aktiengesellschaft

Behringwerke Aktiengeseschaft

Karl-Heinz Wenz

Norbert Heimburger

Gerhardt Kumpe

Eckhard Schuler

Klaus Wellner

A process for removing aromatic heterocyclic compounds from a product-containing solution, in particular a protein solution, by bringing the solution into contact with a support material. The process is preferably carried out following a virus inactivation with acridine or acridine derivatives and makes it possible to remove these virus-inactivating agents from the solution without there being any significant product losses or changes in the biological activity of the solution.

Process for removing aromatic heterocyclic compounds product-containing

A process for the preparation of a pasteurized factor VIII concentrate with high specific activity and stability is described, which comprises adsorbing impurities from the solution containing the factor VIII by at least two-fold adsorption with Al(OH).sub.3, an anion exchanger or Ca.sub.3 (PO.sub.4).sub.2, preferably with two different adsorbents from this group.

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Munich, Georgia

Karl-Heinz Wenz