Illinois Institute of Technology

Karina Tuz

Oscar Juarez

David Do Le Minh

A composition and method for preventing and treating infections caused by enveloped viruses, such as SARS-CoV-2 virus. The invention includes compounds having a catalytic domain of a glycosidase and a binding domain that binds the compound to the surface of the targeted virus. The invention also includes a pharmaceutical formulation comprising the compound and a pharmaceutically acceptable carrier to deliver the active portion of the compound to the infecting virus within an infected human or animal. The pharmaceutical formulation can be an inhalant or a nasal spray to the infected human or animal. The invention also includes methods of using a glycosidase or the catalytic part of a glycosidase to deactivate enveloped virus by removing glycans from the viral surface protein.

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Buffalo Grove, IL, United States of America

Karina Tuz