Elbion Ag

Biotie Therapies Corporation

Karin Steinike

Ute Egerland

Chris Rundfeldt

Hildegard Kuss

Rudolf Schindler

Matthias Olbrich

Norbert Höfgen

Nobert Höfgen

The invention relates to substituted 7-azaindoles, process for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active ingredients for the treatment of disorders which can be influenced by inhibition of phosphodiesterase 4 activity in particular in immunocompetent cells (e.g. macrophages and lymphocytes) by the compounds of the invention.

7-azaindoles and the use thereof as therapeutic agents

The invention relates to substituted 4-, 6- or 7-hydroxyindoles with N-oxide groups, process for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active ingredients for the treatment of disorders which can be influenced by inhibition of phosphodiesterase 4 activity in particular in immunocompetent cells (e.g. macrophages and lymphocytes) by the compounds of the invention.

4-,6- or 7-hydroxyindoles with N-oxide groups and the use thereof as therapeutic agents

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Radebeul, Germany

Karin Steinike