Ciba Specialty Chemicals Corporation

Karin Petzold

Wolfgang Haap

Dietmar Ochs

Marcel Schnyder

Werner Hölzl

Werner H&ouml;lzl

Fernand Hoffstetter

Andreas Mehlin

Fran&ccedil;ois Brugger

Radojka Vukomanovic

Karin M&uuml;hlbauer

J&uuml;rgen Koppold

4-amino-2-(2-pyridyl)pyrimidines as microbicidal active substances

Tetrahydrocarbazoles of formulawhere Q is &#x2014;SO&#x2014;; &#x2014;O&#x2014;; or &#x2014;(CO)&#x2014;; X is &#x2014;(CH)&#x2014;; or &#x2014;N&#x2014;; m is from 1 to 3; t is 0 or 1 and the remaining substituents are as defined herein, are useful as antimicrobial active ingredients.

Tetrahydrocarbazoles, a process for the preparation of those compounds, and the use thereof

The use of compounds of formula (1) is described, in which compounds R, Rand Rare each independently of the others hydrogen; C-Calkyl; C-Ccycloalkyl; C-Calkenyl; C-Ccycloalkenyl; C-Calkynyl, C-Ccycloalkynyl; or unsubstituted or C-Calkyl-, C-Ccylcoalkyl-, C-Calkoxyl-, C-Ccycloakoxy-, halo-, oxo-, carboxy-, carboxy-C-Calkyl ester-, carboxy-C-Ccylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C-Calkylamino- or nitro-substituted phenyl-C-Calkyl, naphthyl-C-Calkyl, phenylcarbonyl-C-Calkyl, naphthylcarbonyl-C-Calkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl, thiophenyl, pyrazolyl, imidazolyl, oxazolyl, thiazolyl, isoxazolyl, isothiazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, 1,2,3-oxadiazolyl, 1,3,4-oxadiazolyl, 1,2,3-thiadiazolyl, 1,3,4-thiadiazolyl, indolyl, pyridyl, pyridazinyl, pyrimidinyl, pyridazinyl, quinolinyl or isoquinolinyl; R, R, Rand Rare each independently of the others hydrogen; C-Calkyl; C-Ccycloalky; C-Calkenyl; C-Ccycloalkenyl; C-Calkynyl; or C-Ccycloalkynyl; and m and n are each independently of the other 0 or 1, for antimicrobial treatment of surfaces. The compounds exhibit a pronounced activity against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are accordingly suitable for the antimicrobial treatment, especially preservation and disinfection, of surfaces.

Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces

4-aminobut-2-ynecarboxylic acid derivatives

Surface-active preparations

Growing community of inventors

Fischingen, Germany

Karin Petzold