Lts Lohmann Therapie-systeme Ag

Isis Pharmaceuticals, Inc.

Karin Ludwig

Markus Krumme

Michael Horstmann

Bodo Asmussen

Karsten Cremer

Hans-Rainer Hoffmann

Michael Roreger

Klaus Schumann

Patrick Mohr

Peter Steinborn

Michael Simon

Tobias Kleudgen

Dieter Anh&auml;user

Christian Hausen

Uwe Bungarten

Adhesive bandages are provided with a water-vapor permeable back layer and an adhesive layer, in which the adhesive layer includes 10 weight percent of a disperse internal phase of hydrophilic particles that are water-swellable in an outer phase that includes at least 10 weight percent of a styrene block copolymer and at least 20 weight percent of an ester resin of colophony, and that can further contain at least one anti-virus substance.

Water-vapor-permeable adhesive bandages

A polymer-based preparation in film form for biphasic release of substances present therein to liquid surroundings, is characterized in that the preparation comprises at least two polymer matrix layers which differ in terms of their construction from polymers, with release taking place rapidly from one of the layers, and release taking place slowly from at least one other layer.

Preparation in film form for biphasic release of pharmacologically active or other substances

A non-reclosable package for products which are prejudicial to health, such as pharmaceutical products. The package comprises a first packaging material element and a second packaging material element. The two packaging material elements are arranged on top of each other. The package has at least one first surface section, at the margin or margins of which the two packaging material elements are releasably connected with each other. At least one cavity, which is enclosed on all sides and receives the product to be packaged, is formed between the two packaging material elements. The package has at least one second surface section lying outside or adjoining the first surface section, and at the margin or margins of which the two packaging material elements are releasably connected with each other. At least one of the two packaging material elements has at least one structure extending within the second surface section and enables the packaging material element(s) to be torn.

Non-reclosable package for products prejudicial to health, as well as process for its production

A package for flat, pliable objects, such as for wafer-shaped or film-shaped drug forms. The package has a carrier layer, a cover layer which is detachably connected to the carrier layer, and a first surface region wherein the carrier layer is not connected to the cover layer and is completely surrounded by a margin area. A cavity, enclosed on all sides, is formed for accommodating an object. The package has a second surface region wherein the carrier layer is not connected to the cover layer. At least one perforation line extends at least partially within the second surface region, and is provided both in the carrier layer and in the cover layer. Severing the perforation line forms a free edge of the cover layer which serves as a gripping aid and enables manual removal of the cover layer from the carrier layer. The disclosure further covers a process for packaging flat, pliable objects by forming the above-described package.

Peelable, child-resistant package for film-shaped drug forms

Film preparation for biphasic release of pharmacologically active or other substances

A sheet-like, film-like or wafer-like preparation for administering substances affecting flavor or odor and/or substances for care and/or curative substances, comprising a coding of these substances in the form of characters and/or graphic symbols or patterns, with the coding being formed by surface areas of differing thickness, is characterized in that the preparation comprises two differently colored, adjacent layers which have surface areas of differing thickness which are complementary to each other.

Preparation consisting of a film, sheet or wafer-shaped form of administration with a two-layered structure and an integrated identification marking

A primary packaging unit for film-like or wafer-like administration forms for oral application with an off-cut of an upper web of packaging material and of an lower web of packaging material is characterized in that a plurality of dosage units of a film-like or wafer-like administration form, individually sealed in flat compartments formed without cold or hot forming of the packaging material and spaced at a distance to one another, are present in a primary packaging unit, and there are perforations between the compartments which enable the separation of individual compartments, if necessary.

Primary packaging unit for film-like or oblate-like administered shapes

The present invention describes a device for the controlled release of active compounds in the gastrointestinal tract with delayed pyloric passage, having a component expandable on contact with gastric juice, which is surrounded by a polymer covering which is permeable to gastric juice and active compounds. The device contains at least one active compound which is present in a multiparticulate preparation which releases the active compound into the gastric juice with a delay. Compared with conventional pharmaceutical forms with delayed pyloric passage, the release of active compound from a device according to the invention can be better controlled; likewise the device can be easily rolled or folded and can be introduced into capsules without problems.

Growing community of inventors

Datzeroth, Germany

Karin Ludwig