Robert Boschgmbh

Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Karin Lemuth

Jochen Hoffmann

Thomas Brettschneider

Steffen Rupp

Kaushal Sagar

Kai Oertel

Bee Keen Gan

Lloyd Ah Qune

Sonja Weishaupt

A sequencing device has at least one sequencing channel configured to fluidically connect a first gap with a second gap. The sequencing channel is formed as a cavity in the region of the first gap and is formed as a pore in the region of the second gap. The pore has a smaller cross section than the cavity.

Sequencing device and method for operating a sequencing device

A device for processing a biological sample includes a first substrate having a first cavity, a second substrate having a second cavity, a filter element having a plurality of perforations, and an electrically conductive structure. The first cavity forms a first chamber segment of a chamber for accommodating the biological sample. The second cavity forms a second chamber segment of the chamber for accommodating the biological sample. The filter element is formed between the first cavity and the second cavity in order to hold back a plurality of organic cells of the biological sample on the plurality of perforations when the biological sample moves between the first cavity and the second cavity through the filter element. The electrically conductive structure is arranged on the filter element and is configured to cause lysis of the organic cells and/or to duplicate and/or detect defined segments of exposed DNA.

Device and method for processing a biological sample and analysis system for analyzing a biological specimen

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Stuttgart, Germany

Karin Lemuth