Sorin Crm Sas

Ela Medical S.a.s.

Ela Medical S.a.

Karima Amara

Thierry Legay

Alaa Makdissi

Ashutosh Ghildiyal

Renzo Dal Molin

Islam Seoudi

Systems, methods, and devices for activating an implantable medical device from a low-power sleep state are provided. One method includes receiving a wake-up signal at a receiver device from a transmitter device. The wake-up signal includes a series of pulses having a pulse pattern encoding a predetermined wake-up code. The wake-up signal is transmitted via intracorporeal communication of electrical pulses conducted by interstitial tissues of a patient's body. The method further includes extracting the wake-up code from the wake-up signal and determining whether the wake-up code corresponds to a stored wake-up value. The method further includes, in response to determining that the predetermined wake-up code corresponds to the stored wake-up value, switching at least one active circuit element of the receiver device from a lower-power sleep state into a higher-power operational state.

System, methods and apparatus for waking an autonomous active implantable medical device communicating by pulses transmitted through the interstitial tissues of the body

A controlled switching module (), for a multielectrode lead for an active implantable medical device, which connects a detection/stimulation electrode () to one or the other conductor () of a two-wire line. Two volatile controlled switches (), for example, complementary MOS associated with at least one non-volatile programmable memory component (), for example, a suspended nanotube cell or a magnetic tunnel junction cell, supply two previously programmed stable open or closed states. A generator maximum-minimum circuit () is coupled to the conductors at the input, and to the controlled switches at the output for selectively controlling them via the corresponding non-volatile memory component ().

Controlled switching module for a multielectrode lead for an active implantable medical device

An autonomous active medical implantable device, with a power supply and a wake-up circuit that responds to receipt of specific pulses transmitted through the interstitial tissues of the body. A transmitter device () generates trains of modulated pulses applied to electrodes (), and a receiver () processes (e.g., filter, amplify and demodulate) pulses collected on electrodes ('). The receiver circuits () are selectively activated from a dormant (sleep) state in which they are not powered by a power source (), to an operational (active) state in which they are powered and able to process (e.g., filter, amplify and demodulate) the collected pulses. A specific wake-up pulse train, configured in a predetermined characteristic pulse pattern, triggers passive wake-up circuits () in the receiver () to switch the receiver circuits from the sleep state to the operational state.

An active implantable medical device including bidirectional communications between a generator and sensors or actuators located at the distal extremity of a lead. A lead () is connected at its proximal end to a generator () and has at the distal end electrodes () able to come in contact with surrounding tissues. A two-wire connection () connects these electrodes to the generator. The lead incorporates transducers () of sensor or actuator type. The generator includes circuits for sending and receiving digital data () capable of producing instructions to one of the transducers and to receive and decode information from one of the transducers in response to a specific instruction produced by the generator. The transducer is able to receive, decode and carry out the aforementioned controls, as well as send data in response.

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Sceaux, France

Karima Amara