Solazyme, Inc.

Terravia Holdings, Inc.

Corbion Biotech, Inc.

Karen Espina

Scott Franklin

George N Rudenko

Aravind Somanchi

Penelope Chua

Xinhua Zhao

Riyaz Bhat

Jeffrey L Moseley

Shane A Brubaker

Tina Huynh

Matthew Shoa-Azar

Trung H Nguyen

Disclosed herein are methods of manufacturing renewable chemicals through the manufacture of novel triglyceride oils followed by chemical modification of the oils. Methods such as transesterification, hydrogenation, hydrocracking, deoxygenation, isomerization, interesterification, hydroxylation, hydrolysis and saponification are disclosed. Novel oils containing fatty acid chain lengths of C8, C10, C12 or C14 are also disclosed and are useful as feedstocks in the methods of the invention.

Heterotrophically cultivated recombinant microalgae

Genetically engineered microbial, e.g.,, cells provide microbial oil useful as a food additive and a source of renewable fuels and industrial chemicals.

Genetically engineered microbial strains including prototheca lipid pathway genes

Recombinant microalgae including sucrose invertase and thioesterase

Methods are disclosed for cultivation of oleaginous microorganisms on feedstocks including depolymerized cellulosic material such as corn stover,, forage, sugar beet pulp and sugar cane bagasse. Also disclosed are methods of manufacturing novel triglyceride oil compositions using cellulosic feedstocks, including oil compositions comprising fatty acids such as those having chain lengths of 8, 10, 12, and 14 carbon atoms.

Methods for producing a triglyceride composition from algae

Novel gene sequences from microalgae are disclosed, as well as novel gene sequences useful in the manufacture of triglyceride oils. Also disclosed are sequences and vectors that allow microalgae to be cultivated on sugar cane and sugar beets as a feedstock. In some embodiments, the vectors are useful for the purpose of performing targeted modifications to the nuclear genome of heterotrophic microalgae.

Nucleic acids useful in the manufacture of oil

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Renewable fuels produced from oleaginous microorganisms

Disclosed herein are obligate heterotrophic microalgae cells containing an exogenous gene. In some embodiments the gene is a sucrose utilization gene, and further disclosed are methods of manufacturing triglyceride oils using sugar cane or sugar beets as a feedstock in a heterotrophic fermentation. In other embodiments the feedstock is depolymerized cellulosic material. Also disclosed are cells that produce medium chain fatty acids at levels not produced in non-recombinant cells of the same species and genus.

Recombinant microalgae cells producing novel oils

Renewable chemical production from novel fatty acid feedstocks

Growing community of inventors

San Francisco, CA, United States of America

Karen Espina