Neuren Pharmaceuticals Limited

Karel Willy Luc Decroos

Martin Bernard Catherine Bousmanne

Cecilia Betti

Clive Blower

Etienne David Frank Philippe Moniotte

Mimoun Ayoub

James Anthony Bonnar

James Murray Shaw

Mathew Peterson

Matthew Peterson

This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.

Compositions of trofinetide

This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders. 

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Ghent, Belgium

Karel Willy Luc Decroos