Toyo Jozo Kabushiki Kaisha

Toyo Jozo Company, Ltd.

Kaoru Morita

Toshiharu Noda

Shigeo Katsuragi

Nobuaki Nakagawa

Masayuki Hori

Susumu Watanabe

Kunio Ohyama

Sadami Kobari

Toyonobu Uzawa

Kikuo Kotani

Masahiko Taniuchi

Nobutaka Fujii

A compound of the formula ##STR1## wherein Y is sulfur or methylene and A is Asn or Asp, or a pharmaceutically acceptable salt thereof is useful for the treatment of calcium metabolic disorders, cardiac disease and ulcers, and for the improvement of cranial circulation.

Calcitonin gene related peptide derivatives

A compound of the formula ##STR1## wherein R is H or H-Ala-NH- and when A is Asp, B is Asp or Glu, C is Leu and D is Val; when A is Asn and B is Gly, C is Phe and D is Gly; when A is Asn, B is Asp or Glu and C is Leu, D is Gly; and when A is Asn, B is Asp or Glu, and C is Phe, D is Val, or a pharmaceutically acceptable salt thereof, is useful for the treatment of calcium metabolic disorders, cardiac disease and ulcers, and for the improvement of cerebral circulation.

Calcitonin-gene-related peptide derivatives

A peptide represented by the following formula: ##STR1## wherein Y means a sulfur atom or methylene group, A stands for Asp or Asn, B denotes Val or Met and C is Asn or Ser, or a salt thereof.

A peptide of the formula ##STR1## wherein A is Tyr or Phe, or a pharmaceutically acceptable salt thereof, is useful for the diagnosis of parathyroid gland function. When A is Tyr, the peptide can be labelled with iodine-125 without losing its PTH activity and without undergoing oxidation upon storage.

[Nle.sup.8, Nle.sup.18, Tyr.sup.34 or Phe.sup.34 ]-h-PTH peptide

Process for the preparation of antibodies

Peptides for assaying human parathyroid hormone

C-Terminal fragment of human chorionic gonadotropin

Growing community of inventors

Shizuoka, Japan

Kaoru Morita