Shibuya Kogyo Co., Ltd.

Panasonic Healthcare Co., Ltd.

Phc Corporation

Kanjun Yamamoto

Hiroshi Yamamoto

Yasuhiko Yokoi

Akifumi Iwama

Shinji Fukui

Atsushi Nakao

Hironobu Sunayama

Jirou Ohnishi

An isolator for cultivating cells including a working chamber having a plurality of gloves arranged side by side into which operator's hands are inserted to operate cells, the working chamber being sectioned into at least an operation area for operating the cells, and an auxiliary working area for opening a packaged auxiliary instrument used to operate the cells, a gas supply unit that supplies gas into the working chamber so that the gas flows downwardly from an upper side in the working chamber, and a gas flow control unit for controlling the flow of the downwardly flowing gas so that the gas flows from the operation area to the auxiliary working area around the gloves, wherein the gas flow control unit has an exhaust hole portion that has an opened area for passing the gas therethrough and is provided at a lower portion of at least the auxiliary working area, and through which the gas in the auxiliary working area is exhausted.

Isolator for cell culture

A gas supply passage is connected to a decontamination liquid supply passage at a tail end portion side from a delivery device, and an on-off valve which opens and closes the gas supply passage is provided. A controller stores a housed weight of the decontamination liquid between a connection point at which the above described gas supply passage is connected to the decontamination liquid supply passage and the above described tail end portion. When a weight of the decontamination liquid is reduced by a total value of a predetermined weight W which should be supplied to the downstream side equipment and the above described housed weight as a result of starting supply of the decontamination liquid to the above described downstream side equipment, the controller opens the above described on-off valve to return the decontamination liquid at the upstream side from the connection point.

Decontamination liquid supply device

An apparatus for controlling an internal pressure of a hermetically sealed chamber at a prescribed pressure level serves to relax pressure changes in the hermetically sealed chamber. The chamber is connected to an inlet passage for supplying air from an external environment through an aseptic filter, an outlet passage for discharging a gas through an aseptic filter, and an inlet valve and an outlet valve for selectively opening and closing the inlet passage and the outlet passage, respectively. The apparatus also includes a controller for controlling the inlet valve and the outlet valve to keep the internal pressure of the chamber at a prescribed positive pressure level. An elastic membrane of silicone rubber which is expanded or retracted depending on a change in the internal pressure of the chamber to relax the pressure change is connected to the outlet passage between the aseptic filter and the outlet valve.

Apparatus for controlling internal pressure of hermetically sealed chamber

Growing community of inventors

Kanazawa, Japan

Kanjun Yamamoto