Postech Foundation

Postech Academy-industry Foundation

Institute for Basic Science

Kangkyun Baek

Kimoon Kim

Narayanan Selvapalam

Young Ho Ko

Erumaipatty Rajagounder Nagarajan

Kyeng Min Park

Jeeyeon Kim

Woo Seong Jeon

Jin Koo Kang

Gyeongwon Yun

Iiha Hwang

Ilha Hwang

Nam Hoon Kim

Jeehong Kim

Jiyeong Lee

Zahid Hassan

Dong Hyun Oh

Sang Yong Jon

Dongwoo Kim

Selvapalam Narayanan

Kyeng-Min Park

Miran Noh

Young-Ho Ko

Jeeyoun Kim

Jin-Koo Kang

Woo-Seong Jeon

Provided are a polymer capsule loaded with transition metal particles having excellent water dispersibility and stability, and a method for preparing the same. Specifically, the polymer capsule loaded with transition metal particles according to the present invention includes a surface-modified polymer capsule surface-modified to thereby have a positive zeta potential in a dispersed state in water; and transition metal particles loaded on a surface of the surface-modified polymer capsule. In addition, a method for preparing a polymer capsule loaded with transition metal particles according to the present invention includes a) preparing a polymer capsule; b) surface-modifying the polymer capsule to prepare a polymer capsule having a positive zeta potential in a dispersed state in water; and c) sequentially adding a water-soluble transition metal precursor and a reducing agent to a water dispersion of the surface-modified polymer capsule obtained in step b).

Polymer capsule having loaded thereon transition metal particles having excellent water dispersibility and stability, and method for preparing same

The present disclosure provides a cucurbituril derivative-bonded solid substrate in which cucurbituril derivatives of Formula 1 are covalently bonded to a modified solid substrate of Formula 2. The cucurbituril derivative provides functional groups which can be used to link biomaterials to the substrate. Protein chips, gene chips, and sensors for biomaterial assays having the cucurbituril derivative-bonded solid substrate are also provided.

Cucurbituril derivative-bonded solid substrate and biochip using the same

Provided are a kit including a first component that is a compound of formula (1) below bound to a first material and a second component that is a ligand bound to a second material, wherein each of the first and second materials is independently selected from the group consisting of a solid phase, a biomolecule, an antioxidant, a chemical therapeutic agent, an anti-histaminic agent, a cucurbituril dendrimer, a cyclodextrin derivative, a crown ether derivative, a calixarene derivative, a cyclophane derivative, a cyclic peptide derivative, a metallic ion, a chromophore, a fluorescent material, a phosphor, a radioactive material, and a catalyst; and the ligand can non-covalently bind to the compound of formula (1); a method of separating and purifying a material bound to a ligand using the compound of formula (1) bound to a solid phase; a method of separating and purifying the compound of formula (1) or a material bound to the compound using a ligand bound to a solid phase; a sensor chip including a compound of formula (1) bound to a first material and a ligand bound to a second material; and a solid-catalyst complex including the compound of formula (1) bound to a first material and a ligand bound to a second material.

Application using non-covalent bond between a cucurbituril derivative and a ligand

The present disclosure provides a rotaxane compound that can be used to separate molecules within a linkage layer formed on a solid substrate of a biochip by a predetermined distance. The compound is represented by Formula 1, in which a compound of Formula 3 vertically passes through a cavity of cucurbituril or its derivative of Formula 2. It further provides gene chips, protein chips and sensors for biomaterial assays which use the rotaxane molecules to allow biomaterials to be immobilized on a linkage layer such that they are regularly spaced apart from each other by a predetermined distance.

Rotaxane compound, rotaxane-bonded solid substrate, and biochip using the same

Growing community of inventors

Pohang, South Korea

Kangkyun Baek