University of Missouri

Rutgers, the State University of New Jersey

Kamlendra Singh

William J Welsh

Youyi Peng

Raymond B Birge

Stefan G Sarafianos

Thomas Walter Comollo

Stanley G Kimani

Vladyslav Kholodovych

Adeyemi O Adedeji

Raymond Birge

Certain compounds of formula I: I and salts including pharmaceutically acceptable salts thereof are disclosed. Also disclosed are pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I and therapeutic methods using a compound of formula I. 

Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents

The present invention relates to compounds, compositions, and methods, for treating subjects suspected of needing treatment for a Nidovirales virus infection. In certain embodiments, the compounds comprise Nidovirales helicase inhibitors that do not significantly affect helicase ATPase enzymatic activity or nucleic acid binding activity of the helicase.

Suppression of SARS replication by SARS helicase inhibitors

Growing community of inventors

Columbia, MO, United States of America

Kamlendra Singh