Quanterix Corporation

Brain Biomarker Solutions in Gothenburg Ab

Kaj Blennow

Jeffrey D Randall

David Wilson

John Henrik Zetterberg

Henrik Zetterberg

The present invention relates to a method for detecting an individual as being at risk of developing a neurodegenerative disease, the method comprising: a) measuring the amount or concentration of neurofilament-light (NfL) in a sample obtained from the individual; and b) detecting the individual as being at risk of developing the disease by comparing the amount or concentration determined in step (a) to the amount or concentration of NfL in a control, wherein an increased value of NfL relative to the control is indicative of the future development of the disease, as well as to uses related thereto.

Methods for detecting an individual as being at risk of developing a neurodegenerative disease

The present invention, in some embodiments, generally relates to methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury. In some embodiments, the brain injury results from a hypoxic event. In some embodiments, methods are provided for determining a measure of the concentration of tau protein in a patient sample containing or suspected of containing tau protein.

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Kungsbacka, Sweden

Kaj Blennow