Generon (Shanghai) Corporation Ltd.

Evive Biotechnology (Shanghai) Ltd

Generon Corporation Ltd.

Evive Biotechnology Ltd

Kaiyang Tang

Cheng Yi Huang

Xiaoqiang Yan

Yuliang Huang

Dongdong Wu

Cheng Huang

Yuilang Huang

The present application provides methods of administering an IL-22 dimer to an individual, such as a human individual, comprising intravenously administering to the individual an effective amount of an IL-22 dimer, wherein the amount of the IL-22 dimer is about 2 &#x3bc;g/kg to about 200 &#x3bc;g/kg (such as about 10 &#x3bc;g/kg to about 45 &#x3bc;g/kg), as well as methods of treating diseases by following such administration methods. Also provided are kits, unit dosages, and articles of manufacture for use in any one of the methods described herein.

Use of IL-22 dimer in manufacture of a medicament for intravenous administration

The present application provides methods of administering an IL-22 dimer to an individual, such as a human individual, comprising intravenously administering to the individual an effective amount of an IL-22 dimer, wherein the amount of the IL-22 dimer is about 2 &#x3bc;g/kg to about 200 &#x3bc;g/kg (such as about 10 &#x3bc;g/kg to about 45 &#x3bc;/kg), as well as methods of treating diseases by following such administration methods. Also provided are kits, unit dosages, and articles of manufacture for use in any one of the methods described herein.

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Shanghai, China

Kaiyang Tang