Basf Se Corporation

Ciba Specialty Chemicals Corporation

Teva Pharmaceutical Industries Limited

Basf Italia S.r.l.

Kai-Uwe Schöning

Walter Fischer

Edoardo Menozzi

Abdel-Ilah Basbas

Gabriele Baisch

Reinhold Öhrlein

Cinzia Tartarini

Jemima Schmidt

Stefan Hauck

Fritz Blatter

Michael Roth

Martin Szelagiewicz

Paul Adriaan Van Der Schaaf

Adalbert Braig

Beate Fröhling

Ulrich Berens

Martin Studer

Tunja Jung

Bruno Rotzinger

Hans Jürg Kirner

Shrirang Bhikaji Hindalekar

Roswell Easton King

Stephan Burkhardt

Werner Hölzl

Gisèle Baudin

Andrea Preuss

Wolfgang Peter

Nicole End

Massimiliano Sala

Markus Grob

Stewart Todd Elder

Anna Bassi

Tania Weyland

Hans-Rudolf Meier

Davide Alvisi

Robert Cordova

James Robbins

Tiziano Nocentini

Alexander Dichtl

Giulia Cocco

Michael Peter Difazio

Joseph A Kotrola

Karin Mühlbauer

Sandra Franziska Mayer

Adriana Edenharter

Werner Holzl

Walid Al-Akhdar

An intermediate of the formula (I) wherein the radicals Rare independently of one another methyl, ethyl or n-propyl, is suitable for preparing a compound of the formula (A) wherein X is a group of the formula (A-I) or (A-II), Y is C-Calkyl, and Z is a direct bond, &#x2014;(CH)&#x2014; or &#x2014;CH&#x2014;S&#x2014;CH&#x2014;. The compounds of the formula (A) are useful for stabilizing an organic material against thermal, oxidative or light induced degradation. 

Sterically hindered amines

The present invention relates to symmetric diesters of hydroxyalkyl-4-hydroxy-tetraalkylpiperidine compounds and their use as light stabilizers. They are compatible with and soluble in coating formulations of different polarity.

Light stabilizers

Disclosed herein is a compound of the formula (I), wherein one or two radicals of the radicals Rare independently of one another C-Calkyloxy or C-Ccycloalkyloxy and the remaining radicals Rare independently of one another hydrogen, C1-Calkyl or C-Ccycloalkyl; the radicals Rand Rare independently of one another hydrogen, C-Calkyl, C-Ccycloalkyl or a group of the formula (II-a) with Rbeing hydrogen, C-Calkyl, C-Ccycloalkyl, C-Calkyloxy or C-Ccycloalkyloxy; Y is C-Calkylene; m is 0 or 1; n is 1, 2 or 3; when n is 1, X is hydrogen, C-Calkyl, C-Ccycloalkyl or a group of the formula (II-a); when n is 2, X is C-Calkylene; when n is 3, X is a group N(Z&#x2014;)with Z being C-Calkyl. 

Sterically hindered amine light stabilizers with a mixed functionalization

A compound of the formula (I) wherein m and n are independently of one another a number from 1 to 50; the ratio of m/n is 1:10 to 10:1, the recurring units X can have the same definition or different definitions, the recurring units Y can have the same definition or different definitions and the recurring units X and Y can have a random, alternating or block distribution; the recurring unit X is a group of the formula (I-a) and the recurring unit Y is a group of the formula (I-b) the radicals Rindependently of one another are C-Calkyl or C-Ccycloalkyl; the radicals Rand Rare independently of one another C-Calkyl; the radicals R3 are independently of one another hydrogen, C-Calkyl or C-Ccycloalkyl. 

Oligomeric light stabilizers with a specific functionalization

A compound of the formula (I), wherein one or two radicals of the radicals Rare independently of one another C-Calkyloxy or C-Ccycloalkyloxy and the remaining radicals Rare independently of one another hydrogen, C-Calkyl or C-Ccycloalkyl; the radicals Rand Rare independently of one another hydrogen, C-Calkyl, C-Ccycloalkyl or a group of the formula (II-a) with Rbeing hydrogen, C-Calkyl, C-Ccycloalkyl, C-Calkyloxy or C-Ccycloalkyloxy; Y is C-Calkylene; m is 0 or 1; n is 1, 2 or 3; when n is 1, X is hydrogen, C-Calkyl, C-Ccycloalkyl or a group of the formula (II-a); when n is 2, X is C-Calkylene; when n is 3, X is a group N(Z&#x2014;)with Z being C-Calkyl. 

A composition, which comprises a) an organic material susceptible to oxidative, thermal or light-induced degradation; and b) a compound of formula I (Formula I) (I) wherein R, R, R, R, R, R, R, R, Rand Rare independently from each other H, C-C-alkyl, C-C-cycloalkyl, phenyl, C-C-alkoxy or halogen; n is 1, 2, 3, or 4; and when n is 1 A is &#x2014;C(=0)-OR', &#x2014;C(=0)-N(R&#x2032;)(R&#x2032;), &#x2014;CN, phenyl, which is unsubstituted or substituted by one or more C-C-alkyl, C-C-alkoxy, C-C-cycloalkyl or halogen, &#x2014;H or &#x2014;S0-phenyl; when n is 2 A is &#x2014;C(=0)-O&#x2014;Z&#x2014;O&#x2014;C(=0)-, &#x2014;C(=0)-N(R&#x2033;)&#x2014;Z&#x2014;N(R&#x2033;)&#x2014;C(=0)- or piperazine-N,N&#x2032;-biscarbonyl. 

5H-furan-2-one derivatives for stabilization of organic material

The disclosure concerns sterically hindered amine light stabilizers (HALS) with low basicity at the nitrogen atom and high thermal stability. They are characterized by their spiro-substitution in the 4-position of the tetramethylpiperidine ring (Spiro-NOR-HALS). These compounds are useful in stabilizing polymers, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation. The compounds are also useful in stabilizing acid catalyzed and ambient cured coatings systems. They are particularly useful when high processing temperatures are additional required.

Sterically hindered amine light stabilizers

The instant invention pertains to novel bi- or tricyclic sterically hindered alkoxyamines, their precursors, a process for their preparation and their use as light stabilizers for polymers or coatings, as flame retardants, as peroxide substitutes (rheology modifiers) or carbon radical scavengers. 

Bi&#x2014;or tricyclic sterically hindered alkoxyamines and process for their preparation

N-substituted Macrocyclic Triazine-HALS Stabilizers.

Stabilizers

The present invention relates to a novel process for the preparation of specific sterically hindered nitroxyl ethers from their corresponding sterically hindered nitroxyl radicals by reacting it with an aldehyde and a hydroperoxide. This nitroxyl ether formation may be carried out from different starting nitroxyl radicals, which are subsequently further reacted to the desired compounds. The compounds prepared by this process are effective as stabilizers for polymers against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.

Process for the preparation of sterically hindered nitroxyl ethers

The present invention relates to a novel process for the preparation of a sterically hindered nitroxyl ether from the corresponding sterically hindered nitroxyl radical by reacting it with a carbonyl compound and a hydroperoxide. The compounds prepared by this process are effective stabilizers for polymers against harmful effects of light, oxygen and/or heat, as flame-retardants for polymers and as polymerization regulators.

Anti-microbial compositions comprising certain imidazolium ionic liquids and non-ionic or anionic surfactants and methods of using said compositions in the preservation of personal care and cosmetic applications are provided.

Anti-microbial compositions

The present invention concerns coloring keratin fibers, especially human hair, with colored metal complexes.

Coloring keratin fibers with metal complexes

The present invention is directed to new crystalline forms of Atorvastatin calcium (2:1), referred to hereinafter as polymorphic Forms X, A, B1, B2, C, D and E. Furthermore, the present invention is directed to processes for the preparation of these crystalline forms and pharmaceutical compositions comprising the crystalline forms.

Crystalline forms of atorvastatin

The present invention relates to an improved process for the preparation of phenolic carboxylic acid derivatives catalysed by biocatalytic esterification, transesterification or amidation of a corresponding lower alkyl ester. Biocatalysis is performed in the presence of suitable enzymes, e.g. hydrolases, especially esterases, amidases, lipases and proteases.

Process for the preparation of phenolic carboxylic acid derivatives by enzymatic catalysis

Growing community of inventors

Oberwil, Switzerland

Kai-Uwe Schöning