Lifecell Corporation

Musculoskeletal Transplant Foundation

The Methodist Hospital

Kai-Roy Wang

Aaron M Barere

Evan J Friedman

Sangwook Park

Israel James Jessop

Christopher Labak

Derek Hugger

Brendan Patrick Collins

Aldona Jedrysiak Spiegel

Yi Heng Chen

Hui Xu

Wenquan Sun

Scott Woodruff

Mark Hayzlett

Hua Wan

Li Ting Huang

Nimesh Kabaria

Patrick Leamy

Yi Chen

Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.

Systems and methods for medical device control

Soft tissue repair grafts are provided for supporting, covering, and/or retaining an implant positioned in the body of a subject. The grafts are particularly suitable for use for pre-pectoral breast reconstruction with a breast implant or tissue expander. The grafts include positional notches for more accurate positioning in a subject. The grafts also include at least one cuff element which is folded to form a reinforced folded edge for suturing the graft more securely to adjacent tissues than previously known grafts. The grafts also include a plurality of arcuate slots which form a plurality of circular patterns arranged concentrically about a focal point, thereby enabling the grafts to expand without tearing and to conform more closely to the implant and/or adjacent body tissues such as the breast pocket, than previously known grafts. Acellular dermal matrices are particularly suitable for making the soft tissue repair grafts.

Soft tissue repair grafts and processes for preparing and using same

Techniques and devices for improved breast surgeries are provided. The devices can include tissue matrix and synthetic meshes for surrounding breast implants or tissue expanders to provide improved implant outcomes for pre-pectoral implantation or other implantation techniques.

Breast treatment device

The present disclosure provides devices and methods for treating breasts. The devices can include an acellular tissue matrix having a predefined shape that allows for complete or enhanced coverage of an anterior portion of a breast implant or tissue expander or to support an implant and/or surrounding tissues.

The present disclosure provides devices and methods for treating the breast. The devices can include an acellular tissue matrix having a predefined shape. The shape can include a first edge with an S-shaped configuration and a second arcuate-shaped edge. The shape alternatively can include a first concave edge and a second convex edge.

Soft tissue repair graft

The present disclosure provides systems and methods for transfer of tissue or other materials such as adipose tissue. The systems and methods can include a vessel and a syringe to facilitate transfer of tissue between one or more vessels and tissue implantation devices.

Syringe filling device for fat transfer

Tissue processing devices are provided. The tissue processing devices can be used to process and transport tissue in a closed and continuous environment. The devices can be used for adipose tissue transfer, including autologous fat grafting.

Tissue processing device and associated systems and methods

Methods, systems, and compositions for treatment are provided. The methods can be used to stretch and completely or nearly completely wrap a composition around an implant or tissue expander. The systems can be used to protect an implant or tissue expander by completely or nearly completely wrapping a composition around the implant or tissue expander. The compositions can be used to completely or nearly completely wrap around an implant or tissue expander to provide support and protection to the implant or tissue expander.

Tissue matrices and methods of treatment

Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen-containing tissue matrix to reduce a human immune response to the tissue matrix. The methods can comprise treatment with alcalase under conditions controlled to produce a desired pliability without unacceptable alteration in collagen structure.

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Jersey City, NJ, United States of America

Kai-Roy Wang