Other

Institute for Systems Biology

Phenogenomics Corporation

Realnetworks Gmbh

Battelle Memorial Institute

The Ohio State University

Ucb S.a.

Celltech R&d Limited

Centre De Recherche Public De La Sante

Intec Science, Inc.

Kai Hua Wang

David J Galas

Leroy E Hood

Chia-Yang Tsai

Patrick R Charmley

Yong Zhou

Fang Lu

John Jay Liljeberg

James C Wallace

Matthew P Fitzgibbon

Rhodora H Argonza-Barrett

Ryan C Smith

Frank N W Lu

Qi Li

Jiajun Chen

Rima McLeod

Richard Evan Gelinas

Kamal El Bissati

Craig Roberts

Clay Braden Marsh

Ying Zhou

Chao Kuang

Haoyu Huang

Melissa Garnet Piper

Martin McPhillie

Colin W G Fishwick

Hernan Alejandro Lorenzi

Taek-Kyun Kim

Mark Hickman

Inyoul Lee

QiGui Li

Tong-Yuan Kuo

Weijia Zhu

Peter Cheng-Shiang Fang

Li-Chuan Chien

Dhimankrishna Ghosh

Yuanyuan Song

Lechang Cheng

Fyaaz Mohammad Barakati

Ji Hoon Cho

Etienne Moussay

Guy Berchem

Weilie Zhou

Disclosed herein; are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.

Compounds and methods for treating, detecting, and identifying compounds to treat apicomplexan parasitic diseases

Provided herein are systems and methods for encoding an unencoded video frame of a sequence of video frames using a condensed coding header format. After a frame is divided into coding blocks and the visual data encoded, the coding block header data for each coding block is combined and encoded. A flag is set in the frame's frame header indicating whether the condensed or non-condensed coding block header format is being used.

Condensed coding block headers in video coding systems and methods

A protocol is provided by which a current block and a neighboring block are identified and the current block is processed. In some variants a deblocking filter is applied with a filtering block size set either to the standard blocksize or to the shared blocksize, depending on whether the shared size of the current and neighboring blocks is smaller than a standard blocksize.

Layered deblocking filtering in video processing systems and methods

A system and method for detecting the occurrence of an event causing multiple hosts to be unresponsive. The system and method including, for a set of hosts providing services to one or more customers of a computing resource service provider, determining one or more subsets of hosts that are unresponsive, determining whether the one or more subsets of hosts that are unresponsive meet a set of criteria for an occurrence of an large-scale event affecting multiple hosts, based at least in part on a determination that the set of criteria is met, initiating a remediation action.

Large-scale event detector

Concentrations of certain miRNA, mRNA and/or protein markers in the biological fluids and/or tissues of a subject are used to determine the probability that the subject does or does not have Posttraumatic Stress Disorder (PTSD). The concentrations of these markers in fluids and/or tissues are different in subjects with PTSD as compared to subjects who do not suffer from this disorder.

Markers and methods for detecting posttraumatic stress disorder (PTSD)

Improved methods to quantitate RNA in biological or other analytical samples employ extended RNAs containing adaptors at the 5' end and polyA sequences coupled to a tag at the 3&#x2032; end. The invention method is particularly useful in quantitating microRNAs as primers can be used that need not complement the non-conserved 3&#x2032; ends of these molecules.

Methods to detect and quantify RNA

Aligned nanowire arrays were coated with semiconductor shell layers, and optionally with noble metal nanoparticles for use as three dimensional gas sensors. The sensors show room-temperature responses to low concentrations of various gases. Arrays containing different sensor types can discriminate among different gases, based upon changes in conductivity and response times.

Aligned, coated nanowire arrays for gas sensing

New markers in the form of miRNA levels in plasma are provided for indicating the presence of CLL in a subject as well as suggesting routes of therapeutic treatment.

Diagnosis and treatment of chronic lymphocytic leukemia (CLL)

Methods, compositions, and devices are disclosed which use microRNA to detect, predict, treat, and monitor physiological conditions such as disease or injury. microRNA are isolated and their differential expression is measured to provide diagnostic information. This information may then be utilized for evaluation and/or treatment purposes.

Methods, compositions, and devices utilizing MicroRNA to determine physiological conditions

Compositions and methods for protecting and administering small RNA to preserve stability are described. The small RNAs may either be in unmodified form or may be chemically modified to enhance stability further.

Compositions for protection and cellular delivery of interfering RNA

The present invention provides nucleic acid molecules, polypeptides, antibodies and methods for the diagnosis and/or treatment of psoriasis.

19.5 polypeptide antibodies useful for diagnosing or treating psoriasis

Antibodies for diagnosing psoriasis

A sampling assembly for simultaneously testing a liquid biological sample for a plurality of hormones and method thereof are described. A sampling membrane includes a dry porous carrier having a proximal end narrower than a distal end and forming a unidirectional liquid flow channel. The distal end includes a plurality of tines arranged and separated by substantially regular spacing. Each tine defines a dye zone including a dye-tagged antigen-specific antibody at a distal end. The sampling membrane further defines a set of focusing recesses along each side of the unidirectional flow channel end and a set of dispersal recesses between and adjacent to each tine. A plurality of test strips each include a dry porous carrier communicatively attached to the distal end of one such tine. Each test strip forms a unidirectional liquid flow channel and includes a testing zone comprising an antigen-specific antibody located distally from the dye zone.

Sampling assembly for simultaneously testing a liquid biological sample for a plurality of hormones and method thereof

A system and method for transacting and manipulating a multi-sequence search using a biological data repository is described. A set of search query parameters specifying a plurality of sequence sets is received. Each sequence set encodes structured biological data values. A search queue is loaded with the search query parameters formatted into a structured database query for each sequence set assigned by search type. A search of the biological data repository is launched for each sequence set. Search results generated responsive to each such structured database query search are retrieved. The search results are received as sequence set information organized and reformatted for each sequence set and search type. A plurality of sequences are aligned using the search results based on one or more structured biological data values having matching characteristics. The aligned sequences are forwarded with matching characteristics indicators.

System and method for transacting and manipulating a multi-sequence search using biological data repositories

A system and method for providing flexible access and retrieval of sequence data from a plurality of biological data repositories is described. A plurality of biological data repositories are maintained. Each data repository contains sequence data stored into structured records uniquely identified. Each data repository is interfaced through a queue handler dynamically locating and selecting at least one such biological data repository and launching a search query against each selected biological data repository. Search query parameters are accepted from a user specifying a search request for a sequence set. Results obtained from a search engine are presented as ordered tables of search results.

System and method for providing flexible access and retrieval of sequence data from a plurality of biological data repositories

Growing community of inventors

San Bruno, CA, United States of America

Kai Hua Wang