Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Kai Hebestreit

Klaus Thome

Sylvia Saecker

Werner Heidt

Carina Horn

Wolfgang Petrich

Jean-Michel Asfour

Gerrit Kocherscheidt

Frederic Wehowski

Claudia Gaessler-Dietsche

Bernd Rösicke

Andreas Weller

Klemens Bardelang

Claudia Gässler-Dietsche

Robert Knapstein

Stefan Lieder

Marina Swan Backhaus

Klaus ThomÉ

A test element analysis system for the analytical examination of a sample is disclosed. The test element analysis system comprises: at least one evaluation device with at least one test element holder for positioning a test element containing the sample and at least one measuring device for measuring a change in a measuring zone of the test element, the change being characteristic for the analyte; at least one electrical heating element configured for electrically heating the test element; at least one electrical power supply for supplying electrical energy to the electrical heating element; at least one temperature sensor connected to the test element holder for detecting a temperature of the test element holder; at least one gap detection device configured for monitoring the electrical energy Esupplied by the electrical power supply to the electrical heating element for reaching a predetermined target temperature measured by the temperature sensor.

Test element analysis system for the analytical examination of a sample

A test element analysis system for an analytical examination of a sample, in particular of a body fluid, is disclosed. The test element analysis system comprises an evaluation device with a test element holder for positioning a test element containing the sample and a measuring device for measuring a change in a measuring zone of the test element, the change being characteristic for an analyte. The test element holder contains contact elements with contact surfaces which allow an electrical contact between contact surfaces of the test element and the contact surfaces of the test element holder. The contact surfaces of the contact elements of the test element holder are provided with an electrically conductive surface containing metallic ruthenium.

Test element analysis system

A test element analysis system for the analytical examination of a sample comprising: at least one evaluation device with at least one test element holder and at least one measuring device for measuring a change in a measuring zone of a test element; at least one barcode reader comprising at least one circuit board having a front side facing the barcode of the test element positioned in the test element holder and a reverse side facing away from the test element, wherein at least one electronic control element of the barcode reader is disposed on the circuit board and wherein the circuit board comprises at least one cavity penetrating the circuit board; at least one camera carrier element; and at least one camera electrically connected to the camera carrier element, with the camera carrier element and the camera being positioned such that the camera observes the barcode through the cavity.

The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement of a fluorophore, wherein the detection medium which contains a fluorophore or a precursor of the fluorophore is admixed with an absorber whose absorbance spectrum superimposes the fluorescence excitation range of the fluorophore. The system consisting of the fluorophore and the absorber, which is produced in the detection medium, has an altered effective fluorescence excitation range with an altered fluorescence excitation maximum. Illumination with fluorescence excitation light can take place within the range of this altered excitation maximum. The measured signal obtained from determining fluorescence emission exhibits only low dependence on the wavelength of the excitation light.

Fluorescence spectroscopy in absorbing media

An integrated test element () is proposed for detecting for detecting at least one analyte in a sample (), in particular in a liquid sample (). The integrated test element () has a carrier element (), with an application face () on which at least one organic electroluminescent component () is applied. Furthermore, at least one indicator substance () is applied on the application face (), which indicator substance () alters at least one optical characteristic, in particular an emission characteristic (e.g. a fluorescence characteristic), when it comes into contact with the at least one analyte. Furthermore, the integrated test element () has at least one photodetector element ().

Integrated test element

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Heidelberg, Germany

Kai Hebestreit