Leland Stanford Junior University

Kai Cheng

Hongjie Dai

Zhen Cheng

Hao Chen

Xuechuan Hong

Alexander Antaris

A stereo imaging system includes a pair of folded-parallel-light-channel (FPLC) units arranged to provide a virtual left side view and a virtual right side view of a scene. Each FPLC unit includes a fixed lens unit adapted to focus reflected light comprising an image of a scene to an image sensor and a light-redirecting unit comprising a reflector adapted to define a parallel image reflection path to the fixed lens unit via a collimated light beam.

Folded parallel-light-channel based stereo imaging system

Disclosed is a small molecule dye for use in imaging in the near-infrared window, namely between 1000 nm-1700 nm wavelength. The present dyes are also useful for photoacoustic imaging and photothermal therapy. The dyes have a structure of a D-A-D (donor-acceptor-donor) fluorescent compound core and side chains rendering the compounds water soluble and easily conjugated to hydrophilic polymers and/or targeting ligands. Further disclosed is compound, CH1055 that can be PEGylated, conjugated to a targeting ligand, or conjugated to taurine. Key steps utilized to assemble the core structure of the target included a cross-Suzuki coupling reaction, iron reduction and N-thionylaniline induced ring closure. Four carboxylic acid groups were introduced into the donor-acceptor-donor (D-A-D) type fluorescent compound to impart a certain aqueous solubility and to allow facile conjugation to targeting ligands.

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Mountain View, CA, United States of America

Kai Cheng