Thorlabs Gmbh

Jörn Wollenzin

Dierck Hillmann

Alex Cable

Jeffrey S Brooker

James Jiang

Peter Koch

Gereon Hüttmann

Helge Sudkamp

Kirk Gossage

Jason Matthew Mills

Gesa Lilith Franke

Ross Johnstone

Laura Hinkel

A parallel detecting optical coherence tomography (OCT) setup and method, in which the light paths of the illumination of the sample and of the detection of the backscattered light do not use the same apertures. The separation of illumination and detection apertures filters these disturbing reflexes from the backscattered light of the sample and significantly increases image quality.

Method for filtering reflexes in full-field setups for ophthalmologic imaging by separated illumination and detection apertures

Disclosed are several technical approaches of using low coherence interferometry techniques to create an autofocus apparatus for optical microscopy. These approaches allow automatic focusing on thin structures that are positioned closely to reflective surfaces and behind refractive material like a cover slip, and automated adjustment of focus position into the sample region without disturbance from reflection off adjacent surfaces. The measurement offset induced by refraction of material that covers the sample is compensated for. Proposed are techniques of an instrument that allows the automatic interchange of imaging objectives in a low coherence interferometry autofocus system, which is of major interest in combination with TDI (time delay integration) imaging, confocal and two-photon fluorescence microscopy.

Microscopy system with auto-focus adjustment by low-coherence interferometry

Growing community of inventors

Lübeck, Germany

Jörn Wollenzin