Novartis Ag

Abbvie Deutschland Gmbh and Co Kg

Jörg Ogorka

Jörg Breitenbach

Ulrich Westedt

Martin Knobloch

Harald Hach

Norbert Steiger

Ralf Altenburger

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The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, (b) at least one polymeric binder, and (c) at least one pharmaceutically acceptable non-ionic surfactant. The invention provides imatinib dosage forms with high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an essentially pH-independent fashion, and extended release imatinib dosage forms.

Melt-processed imatinib dosage form

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Steinen, Germany

Jörg Ogorka